Results 41 to 50 of about 156,715 (315)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
International Conference on Mechanical Engineering and Technology
, 2012 The volume includes a set of selected papers extended and revised from the 2011 International Conference on Mechanical Engineering and Technology, held on London, UK, November 24-25, 2011.
Zhang, Tianbiao
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A critical study on the strategy for capital machinery manufacturing SMEs in Bangladesh [PDF]
, 2005 This study presents the results of a research programme carried out on small and medium sized enterprises (SME) of manufacturing industrial capital machinery in Bangladesh.
Islam, Mollah Shahidul
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AIP Advances, 2019 Selective laser melting (SLM) produces complex physical behaviors. After laser melting, the molten pool condenses with an uneven surface, which influences the next powder spreading process and affects the quality of the final product.
Liwei Chen +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The 8th International Conference on Advances in Construction Machinery and Vehicle Engineering
This open access book presents select contributions from the 8th International Conference on Advances in Construction Machinery and Vehicle Engineering (ICACMVE 2023), focusing on the recent advances and best practices of Construction Machinery and ...
core +1 more source
Enhancing the effectiveness of thermal water consumption via heat pumping
Apstract: Applied Studies in Agribusiness and Commerce, 2015 Renewable technologies and the extension of their scope of usage basically has to face the general obstacles like any other novelties newly introduced to the market.
János Nagygál +4 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The 9th International Conference on Advances in Construction Machinery and Vehicle Engineering
This open access book presents the proceedings of the 9th International Conference on Advances in Construction Machinery and Vehicle Engineering (ICACMVE 2024), highlighting the latest advancements and innovative practices in the field.
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