Results 61 to 70 of about 152,111 (265)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

PENERAPAN WORK PREPARATION DAN INTENSITAS PENDAMPINGAN PADA CAPAIAN PRESTASI PRAKTIK PEMESINAN MAHASISWA JURUSAN MESIN FAKULTAS TEKNIK UNIVERSITAS NEGERI YOGYAKARTA

Cakrawala Pendidikan: Jurnal Ilmiah Pendidikan, 2010
: Work Preparation and Coaching Intensity to Improve Mechanical Engineering Students’ Academic Achievement in the Machinery Practicum in the Engineering Faculty of the Yogyakarta State University.
Thomas Sukardi
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

INTEGRATING MECHANICAL AND ELECTRONIC ENGINEERING FOR ENHANCED AGRICULTURAL MACHINERY EFFICIENCY

The rapid advancement of science and technology has ushered in an era of intelligent and automated agricultural production. Concurrently, the domains of machinery and electronic engineering have evolved towards greater sophistication in intelligence and automation, driving the ever-growing demand for control technology.
openaire   +3 more sources

Effects of Deformation Parameters on Microstructure and Mechanical Properties of a 1300 MPa Grade Steel for Engineering Machinery

Journal of Materials Research and Technology
A 1300 MPa grade engineering steel was processed by a two-stage deformation schedule to investigate the effects of second-stage deformation temperature and strain on transformation behavior, final microstructure, and tensile response. After austenitization, the second deformation step was conducted at 850 and 920 °C with strains of 30% and 50 ...
Juan Xiao, Qi Zhang, Xiaolong Gan, Junyu Tian, Wei Huang, Guojun Ma, Feng Huang, Guang Xu   +7 more
openaire   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Tuning electro-thermo-mechanical coupling in electroactive nanocomposites for self-oscillating solid-state heat pumps

npj Flexible Electronics
Solid-state cooling based on the electrocaloric effect (ECE) offers low power consumption and zero greenhouse gas emissions. Among various designs of electrocaloric cooling devices, the flexible self-oscillating EC heat pumps, enabled by synergistic ECE ...
Ruhong Luo, Feiyu Zhang, Cenling Huang, Donglin Han, Chengwei Ye, Binzhou Sun, Lu Yu, Shanyu Zheng, Feihong Du, Qiang Li, Yifan Zhao, Zhenhua Ma, Yezhan Lin, Yike Wang, Guangyu Lu, Xi Zhao, Shaochun Tang, Tiannan Yang, Xiaoshi Qian   +18 more
doaj   +1 more source

Charging valve of the full hydraulic braking system

Advances in Mechanical Engineering, 2016
It is known that the full hydraulic braking system has excellent braking performance. As the key component of the full hydraulic braking system, the parameters of the accumulator charging valve have a significant effect on the braking performance.
Jinshi Chen, Xinhui Liu, Tongjian Wang, Xun Gong, Haixin Sun, Guoqiang Wang, Wei Chen   +6 more
doaj   +1 more source

Development of a Small-Scale Plastic Recycling Technology and a Special Filament Product for 3D Printing

International Journal of Engineering and Management Sciences, 2019
In our days, the fight against pollution has become a real challenge for the state. recycling is one of the solutions that is adopted in several nations to reduce the rate of plastic discarded in nature.
Alaeddine Oussai , Zoltán Bártfai, László Kátai, István Szalkai   +3 more
doaj   +1 more source