Results 71 to 80 of about 152,111 (265)

Farm Machinery & Mechanization:\\An Engineering Logic

open access: yes
Agricultural engineering is not only about machines—it is about connecting life andlogic. It unites biology, engineering, and the environment into one system that sustainsthe worlds food supply. As a teacher and researcher in mechanization, I saw a need fora resource that explains not only how machines work, but why they exist—rooted in thebiology of ...
openaire   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Novel Weft-Knitted Strain Sensors for Motion Capture

open access: yesMicromachines
Functional electrical stimulation (FES) aims to improve the gait pattern in cases of weak foot dorsiflexion (foot lifter weakness) and, therefore, increase the liveability of people suffering from chronic diseases of the central nervous system, e.g ...
Susanne Fischer   +9 more
doaj   +1 more source

A modified squeeze equation for predicting the filling ratio of nanoimprint lithography

open access: yesNano Convergence, 2017
A numerical method using the modified squeeze model is proposed in this paper in order to overcome the limitation of the established squeeze equation and obtain filling ratios for nanoimprint lithography (NIL).
JiHyeong Ryu   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Farm Machinery & Mechanization: An Engineering Logic

open access: yes
Agricultural engineering is not only about machines—it is about connecting life andlogic. It unites biology, engineering, and the environment into one system that sustainsthe worlds food supply. As a teacher and researcher in mechanization, I saw a need fora resource that explains not only how machines work, but why they exist—rooted in thebiology of ...
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Triboelectric nanogenerator based on a water droplet spring with a concave spherical surface for harvesting wave energy and detecting pressure

open access: yesNanotechnology Reviews, 2023
Wang Weiyuan   +5 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

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