Results 51 to 60 of about 147,466 (260)

Nonlinear forced vibration analysis of composite beam combined with DQFEM and IHB

open access: yesAIP Advances, 2020
In this paper, a forced vibration model of composite beams under the action of periodic excitation force considering geometric nonlinearity is proposed. For the strain–displacement relationship, Timoshenko beam theory is used, and the element and system ...
Kwangchol Ri   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

PENERAPAN WORK PREPARATION DAN INTENSITAS PENDAMPINGAN PADA CAPAIAN PRESTASI PRAKTIK PEMESINAN MAHASISWA JURUSAN MESIN FAKULTAS TEKNIK UNIVERSITAS NEGERI YOGYAKARTA

open access: yesCakrawala Pendidikan: Jurnal Ilmiah Pendidikan, 2010
: Work Preparation and Coaching Intensity to Improve Mechanical Engineering Students’ Academic Achievement in the Machinery Practicum in the Engineering Faculty of the Yogyakarta State University.
Thomas Sukardi
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Optimal solution for the single-beam bridge crane girder using the Moth-Flame algorithm

open access: yesVojnotehnički Glasnik
Introduction/purpose: The paper analyses and optimizes the welded I-girder of the single-beam bridge crane with a U-profile as the top flange. This solution is to provide a lighter carrying structure, so the main goal is to minimize the weight of the ...
Goran V. Pavlović   +4 more
doaj   +1 more source

Supersonically Spray-Coated Colloidal Quantum Dot Ink Solar Cells

open access: yesScientific Reports, 2017
Controlling the thickness of quantum dot (QD) films is difficult using existing film formation techniques, which employ pre-ligand-exchanged PbS QD inks, because of several issues: 1) poor colloidal stability, 2) use of high-boiling-point solvents for QD
Hyekyoung Choi   +5 more
doaj   +1 more source

Simulation-Based Development of a New Cylindrical-Cavity Microwave-Plasma Reactor for Diamond-Film Synthesis

open access: yesCrystals, 2019
A 2.45 GHz microwave-plasma chemical-vapor deposition (MPCVD) reactor was designed and built in-house by collaborating with Guangdong TrueOne Semiconductor Technology Co., Ltd.
Qijun Wang   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Prospective increase in the heat pump’s efficiency through arrangement in a three-temperature system

open access: yesAdvances in Mechanical Engineering, 2019
Analysis of three-temperature heating system has revealed the apparent advantages and disadvantages that the combination of thermodynamic systems has in future development with respect to environmental and economic issues.
Tomáš Stejskal   +4 more
doaj   +1 more source

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