Results 261 to 270 of about 4,424,668 (298)

The regulation of RANKL by mechanical force

Journal of Bone and Mineral Metabolism, 2020
Receptor activator of nuclear factor-κB ligand (RANKL) is a key mediator of osteoclast differentiation and bone resorption. Osteoblast-lineage cells including osteoblasts and osteocytes express RANKL, which is regulated by several different factors, including hormones, cytokines, and mechanical forces.
Fumiyuki, Sasaki, Mikihito, Hayashi, Takehito, Ono, Tomoki, Nakashima   +3 more
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Mechanical forces and the 3D genome

Current Opinion in Structural Biology, 2023
Traditionally, the field of genomics has been studied from a biochemical perspective. Besides chemical influences, cells are subject to a variety of mechanical signals from their surrounding tissue microenvironment. These mechanical signals can not only cause changes to a cell's physical structure but can also lead to alterations in their genomes and ...
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Fibroblast responses to mechanical forces

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 1998
The repair and maintenance of connective tissues is performed predominately by a mesenchymal cell known as a fibroblast. The activity of this cell is regulated, in part, by changes in the mechanical environment in which it resides.
Eastwood, M., McGrouther, D. A., Brown, R. A.   +2 more
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Mechanical Forces in Transformers

Transactions of the American Institute of Electrical Engineers, 1927
In this paper a method of calculating the mechanical forces in transformers, based on mutual reactance between coils, is presented. A formula for the mutual inductance between coaxial solenoids is developed and from this expression the formula for the mechanical force between concentric cylindrical transformer coils is derived.
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Gyroscopic forces for mechanical manipulators

2016 IEEE International Conference on Advanced Intelligent Mechatronics (AIM), 2016
It has long been a challenge to control the end-effector trajectory of mechanical manipulators using only taskspace parameterization. While there exist some taskspace control strategies (such as the potential energy shaping) that guarantee the convergence of the end-effector to the target point without any inverse transformations, how to make the end ...
Nan Wei, Soo Jeon
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Force-linear mechanisms

Mechanism and Machine Theory, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Mechanics of forced unfolding of proteins

Acta Biomaterialia, 2009
We describe and solve a two-state kinetic model for the forced unfolding of proteins. The protein oligomer is modeled as a heterogeneous, freely jointed chain with two possible values of Kuhn length and contour length representing its folded and unfolded configurations.
Tianxiang, Su, Prashant K, Purohit
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Force analysis of the patellar mechanism

Journal of Orthopaedic Research, 1987
AbstractThe aim of this study is an experimental evaluation of a force analysis of the patellar mechanism based on the assumption that patellofemoral contact is frictionless. At first, the geometric characteristics of contact surfaces, a prior knowledge of which is necessary for quantitative analysis, were measured from radiographs of 42 fresh‐frozen ...
A M, Ahmed, D L, Burke, A, Hyder
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Mechanisms of mechanical force aggravating periodontitis: A review

Oral Diseases, 2023
Abstract Periodontitis is a widespread oral disease accompanied by uncontrolled inflammation‐related tissue destruction. Periodontitis is related to various factors. Among them, occlusal trauma can aggravate the severity of periodontitis and has been attracting a great deal of attention.
Xinran Liu, Jiaxin Li, Yuan Yue, Jinle Li, Min Wang, Liang Hao   +5 more
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Gene Regulation by Mechanical Forces

Endothelium, 1997
Endothelial cells are subjected to various mechanical forces in vivo from the flow of blood across the luminal surface of the blood vessel. The purpose of this review was to examine the data available on how these mechanical forces, in particular cyclic strain, affect the expression and regulation of endothelial cell function.
B O, Oluwole, W, Du, I, Mills, B E, Sumpio   +3 more
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