Results 271 to 280 of about 4,424,668 (298)
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Microtubules as mechanical force sensors
Biosystems, 2007Microtubules are polymers of tubulin subunits (dimers) arranged on a hexagonal lattice. Each tubulin dimer comprises two monomers, the alpha-tubulin and beta-tubulin, and can be found in two states. In the first state a mobile negative charge is located into the alpha-tubulin monomer and in the second into the beta-tubulin monomer.
Ioannis Karafyllidis +1 more
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Mechanical forces in skin disorders
Journal of Dermatological Science, 2018Mechanical forces are known to regulate homeostasis of the skin and play a role in the pathogenesis of skin diseases. The epidermis consists of keratinocytes that are tightly adhered to each other by cell junctions. Defects in keratins or desmosomal/hemidesmosomal proteins lead to the attenuation of mechanical strength and formation of intraepidermal ...
Hans I-Chen Harn +2 more
exaly +3 more sources
Activating catalysts with mechanical force
Nature Chemistry, 2009Homogeneously catalysed reactions can be 'switched on' by activating latent catalysts. Usually, activation is brought about by heat or an external chemical agent. However, activation of homogeneous catalysts with a mechanical trigger has not been demonstrated.
Piermattei, A. +2 more
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Dealing with mechanics: mechanisms of force transduction in cells
Trends in Biochemical Sciences, 2004Physical cues, such as forces applied to a cell membrane or the stiffness of materials to which cells adhere, are increasingly recognized as essential determinants of biological function, and mechanical stimuli can be as important as chemical stimuli in determining tissue fate or contributing to pathological states. The physical environment of the cell
Paul A, Janmey, David A, Weitz
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Mechanical work as predictor of force enhancement and force depression
Journal of Biomechanics, 2009The steady-state force following active muscle shortening or stretch differs from the maximum isometric force associated with the final length. This phenomenon proves that the isometric force production is not only dependent on current muscle length and length time derivative, but depends on the preceding contraction history.
Natalia, Kosterina +2 more
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Molecular Mechanism of Apoptosis Induced by Mechanical Forces
2005In all biological systems, a balance between cell proliferation/growth and death is required for normal development as well as for adaptation to a changing environment. To affect their fate, it is essential for cells to integrate signals from the environment.
Michael H, Hsieh, Hiep T, Nguyen
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Forced into shape: Mechanical forces in development and homeostasis
Seminars in Cell and Developmental Biology, 2021Yanlan Mao, Giulia Paci
exaly
Mechanical behavior and modeling of grinding force: A comparative analysis
Journal of Manufacturing Processes, 2023Zafar Said, Changhe Li, Zongming Zhou
exaly