Results 91 to 100 of about 110,588 (202)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effect of Hydrogel Matrix and Fluid Shear Stress on the Behavioral Regulation of Mesenchymal Stem Cells

Small Structures
Development of a micromodel that recapitulates multiple mechanical properties to mimic the complex mechanical microenvironment is crucial for cell‐based research. Herein, a microsystem combining structure of hydrogel matrix and acoustic streaming (AS) to
Shenghui Kang, Xiaoyu Wu, Hang Qi, Kai Yang, Ruoyu Feng, Wenlan Guo, Chen Sun, Xuexin Duan, Yanyan Wang   +8 more
doaj   +1 more source

REVIEW ARTICLE Engineering bio-inks for 3D bioprinting cell mechanical microenvironment. [PDF]

Int J Bioprint, 2023
Yang Y, Jia Y, Yang Q, Xu F.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

How the mechanical microenvironment of stem cell growth affects their differentiation: a review. [PDF]

Stem Cell Res Ther, 2022
Zhang X, Zhang S, Wang T.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Cellular mechanometabolism: stimuli and implications

EMBO Reports
While much is known about the effects of the chemical microenvironment on cellular metabolism, mechanical cues have emerged as critical stimuli of intracellular metabolic pathways. Mechanical signals from the extracellular matrix (ECM), neighboring cells,
Ismael Ortiz, Santiago Lopez, Raghu Vamsi Kondapaneni, Jose V Hernandez, Keefer Boone, Cynthia A Reinhart-King   +5 more
doaj   +1 more source

The Mechanical Microenvironment Regulates Axon Diameters Visualized by Cryo-Electron Tomography. [PDF]

Cells, 2022
Ma D, Deng B, Sun C, McComb DW, Gu C.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

[Erratum] Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells (Review). [PDF]

Mol Med Rep, 2021
Li Y, Wang J, Zhong W.
europepmc   +1 more source