Results 201 to 210 of about 27,702,308 (366)

Crystal-Plasticity-Based Micro-Mechanical Model for Simulating Plastic Deformation of TC4 Alloy. [PDF]

Materials (Basel)
Chen H, Li W, Qian Z, Mi D, Wu Y, Zhang S, Wu C, Li K, Tang T, Li D.   +9 more
europepmc   +1 more source

Elucidating the signal for contact guidance contained in aligned fibrils with a microstructural-mechanical model. [PDF]

J R Soc Interface, 2022
Bersie-Larson LM, Lai VK, Dhume RY, Provenzano PP, Barocas VH, Tranquillo RT.   +5 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Mechanical model and constructional behavior for center diaphragm in shallow tunnel. [PDF]

Sci Rep
Wang R, Wang Z, Fan W.
europepmc   +1 more source

A chemo-mechanical model of endoderm movements driving elongation of the amniote hindgut.

Development, 2023
Oikonomou P, Cirne HC, Nerurkar NL.
europepmc   +1 more source

The Utilization of a Coupled Electro-Thermal-Mechanical Model of High-Voltage Electric Pulse on Rock Fracture. [PDF]

Materials (Basel), 2023
Feng W, Rao P, Nimbalkar S, Chen Q, Cui J, Ouyang P.   +5 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Patient-specific visco-hyperelastic mechanical model for breast tumor localization in surgical planning. [PDF]

Bioeng Transl Med
Alfano F, Navas P, Lamata P, García KF, Ortuño JE, Zamora OB, Lizarraga S, Santos A, Pascau J, Goicolea JM, Ledesma-Carbayo MJ.   +10 more
europepmc   +1 more source

Author Correction: Proposal for a mechanical model of mobile shales. [PDF]

Sci Rep, 2022
Soto JI, Heidari M, Hudec MR.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source