Results 191 to 200 of about 27,702,308 (366)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A mechanical model based on watermelons for the study of dynamic cranial remolding orthoses. [PDF]

Sci Rep
Veloso F, Morais P, Torres H, Fritze A, Rüdiger M, Hahn G, Pinho ACM, Correia-Pinto J, Vilaça JL.   +8 more
europepmc   +1 more source

A structural bio-chemo-mechanical model for vascular smooth muscle cell traction force microscopy. [PDF]

Biomech Model Mechanobiol, 2023
Flanary SM, Barocas VH.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Mechanical modelling of wood microstructure, an engineering approach

, 1997
The macroscopic elastic behaviour of wood derives from the mechanical performance of the cells which form its microstructure. Numerical finite element models are presented which relate the elastic properties of the wood continuum to local cell ...
Stol, K.A., Astley, R.J., K A Stol, Harrington, J.J., R J Astley, J J Harrington   +5 more
core  

Nonlinear seepage mechanical model and bifurcation analysis for fluid-solid coupling in fractured rock mass. [PDF]

Sci Rep
Zhengzheng C, Mengqi X, Tao R, Feng D, Zhenhua L, Wenqiang W.   +5 more
europepmc   +1 more source

A mesoscale mechanical model of cellular interactions. [PDF]

Biophys J, 2021
DiNapoli KT, Robinson DN, Iglesias PA.
europepmc   +1 more source

A mechanical model for failures in shear of members without transverse reinforcement based on development of a critical shear crack

, 2018
Francesco Cavagnis, M. F. Ruiz, A. Muttoni   +2 more
semanticscholar   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Multi-Scale Analysis Model of Thermal-Mechanical Damage Effect in High-Power Continuous-Wave Laser Irradiation of CFRP Laminates

, 2017
A multi-scale analysis model which can reflect thermal-mechanical damage effects,such as ablation, pyrolysis and delamination within layers in the high-power continuous-wave laser irradiation of carbon fiber reinforced polymer(CFRP)laminates is built.The
Zhao Weina, Huang Chenguang, Song Hongwei, Huang Yihui   +3 more
core