Results 171 to 180 of about 29,278,787 (347)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Nonlinear seepage mechanical model and bifurcation analysis for fluid-solid coupling in fractured rock mass. [PDF]

Sci Rep
Zhengzheng C, Mengqi X, Tao R, Feng D, Zhenhua L, Wenqiang W.   +5 more
europepmc   +1 more source

Elucidating the signal for contact guidance contained in aligned fibrils with a microstructural-mechanical model. [PDF]

J R Soc Interface, 2022
Bersie-Larson LM, Lai VK, Dhume RY, Provenzano PP, Barocas VH, Tranquillo RT.   +5 more
europepmc   +1 more source

A mechanical model for failures in shear of members without transverse reinforcement based on development of a critical shear crack

, 2018
Francesco Cavagnis, M. F. Ruiz, A. Muttoni   +2 more
semanticscholar   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Crystal-Plasticity-Based Micro-Mechanical Model for Simulating Plastic Deformation of TC4 Alloy. [PDF]

Materials (Basel)
Chen H, Li W, Qian Z, Mi D, Wu Y, Zhang S, Wu C, Li K, Tang T, Li D.   +9 more
europepmc   +1 more source

A chemo-mechanical model of endoderm movements driving elongation of the amniote hindgut.

Development, 2023
Oikonomou P, Cirne HC, Nerurkar NL.
europepmc   +1 more source

The Utilization of a Coupled Electro-Thermal-Mechanical Model of High-Voltage Electric Pulse on Rock Fracture. [PDF]

Materials (Basel), 2023
Feng W, Rao P, Nimbalkar S, Chen Q, Cui J, Ouyang P.   +5 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Mechanical model and constructional behavior for center diaphragm in shallow tunnel. [PDF]

Sci Rep
Wang R, Wang Z, Fan W.
europepmc   +1 more source