FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Mechanical Model of Tensile Loading of Geotechnical Reinforcement Materials. [PDF]
Materials (Basel)Liu H +6 more
europepmc +1 more source
Mechanical model of steady-state and inflammatory conditions in patients with relapsing polychondritis: A review. [PDF]
Medicine (Baltimore), 2022 Shimizu J, Suzuki N.
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A mechanical model for lateral and axial impacts and quantification of effect on viability of SHSY5Y neuroblastoma cells. [PDF]
Sci RepAkhtaruzzaman R +5 more
europepmc +1 more source
Improved thermal conductivity of polyurethane (PU)-/SiC composite fabricated via solution casting method and its mechanical model for prediction and comparison. [PDF]
Heliyon, 2023 Somdee P, Ansari MA, Szabo T, Marossy K.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Quantifying fracture roughness effects on coal mine spontaneous combustion through a coupled thermos hydro mechanical model. [PDF]
Sci RepLu G, Zhao G, Yu L, Zhang M, Wang X.
europepmc +1 more source
A coarse-grained mechanical model for folding and unfolding of tropoelastin with possible mutations. [PDF]
Acta Biomater, 2021 Florio G +3 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source