Results 91 to 100 of about 2,290,689 (312)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Multimaterial Scaffold With Tunable Properties: Toward Bone Tissue Repair

Advanced Science, 2018
Polyetheretherketone (PEEK)/β‐tricalcium phosphate (β‐TCP) scaffolds are expected to be able to combine the excellent mechanical strength of PEEK and the good bioactivity and biodegradability of β‐TCP.
Pei Feng, Ping Wu, Chengde Gao, Youwen Yang, Wang Guo, Wenjing Yang, Cijun Shuai   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A MEMS viscometer for unadulterated human blood [PDF]

, 2010
The design and theoretical modelling of an oscillating micro-mechanical-viscometer designed for the measurement of whole unadulterated human blood, is described. The proposed device utilises the dependence of the squeeze-film damping ratio on properties
Andrews, Bandey, Blech, Boskovic, Burg, C.R. Chatwin, Chu, Cross, de Simone, Den Hartog, Fertis, Gabrielson, Hausler, Jones, Kajima, Kim, Kim, Macosko, Oden, O’Neil, P.D. Smith, Petersen, Puers, R.C.D. Young, Roark, Romoscanu, Rosenson, Saulson, Shin, Shin, Singer, Steidel, Vellekoop, Vidic, Wang, Winther   +35 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Error Model for Autonomous Global Positioning Method Using Polarized Sky Light and True North Measurement Instrument

Applied Sciences
Long-distance navigation requires global positioning methods to have complete autonomy, particularly when the Global Positioning System is unavailable.
Yinlong Wang, Jinshan Li, Yi Luo, Jinkui Chu   +3 more
doaj   +1 more source

A tough high performance composite matrix [PDF]

, 1992
This invention is a semi-interpenetrating polymer network which includes a high performance thermosetting polyimide having a nadic end group acting as a crosslinking site and a high performance linear thermoplastic polyimide. An improved high temperature
Johnston, Norman J., Pater, Ruth H.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

An Autonomous Mobile Measurement Method for Key Feature Points in Complex Aircraft Assembly Scenes

Machines
Large-scale measurement of key feature points (KFPs) on an aircraft is essential for coordinated movement of locators, which is critical to the final assembly accuracy.
Yang Zhang, Changyong Gao, Shouquan Sun, Xiao Guan, Yanjun Shi, Wei Liu, Yongkang Lu   +6 more
doaj   +1 more source