Results 111 to 120 of about 789,404 (319)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Mechanical performance of acetate lacquer from acacia mangium [PDF]

open access: yes, 2019
Cellulose comprises about 40–50 % of the composition of wood, making it one of the most abundant organic polymers on earth. Cellulose is very versatile in terms of application, with a wide array of products fabricated, including the chemically modified ...
Liew, Kang Chiang   +2 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Performance of a Wave Energy Converter with Mechanical Energy Smoothing [PDF]

open access: yes, 2011
A wave energy converter which uses a power balancing mechanism for turning intermittent and irregular wave motion input to smoothed continuous electrical power output is studied by combined scale-model testing and numerical simulation.
Josefsson, Andreas   +3 more
core  

Mechanical characterization of glassy polymers : quantitative prediction of their short- and long-term responses [PDF]

open access: yes, 2012
In this chapter the relevant phenomena that dominate the mechanical performance of polymer glasses are discussed. Mechanical properties as measured in short-term experiments are directly linked to their long-term performance. The molecular processes that
Möller, M.   +4 more
core   +1 more source

A Modeling Approach With Spatial Basis Functions Learning and Temporal Dynamic Online Modeling for Time-Varying Distributed Parameter Processes

open access: yesIEEE Access, 2019
Currently, most of existing data-driven modeling methods for distributed parameter systems (DPSs) are offline and do not take the intrinsic structure of streaming data into account.
Xinjiang Lu, Jie Xu, Chao-Jun Zhou
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Federated Analytics With Data Augmentation in Domain Generalization Toward Future Networks

open access: yesIEEE Transactions on Machine Learning in Communications and Networking
Federated Domain Generalization (FDG) aims to train a global model that generalizes well to new clients in a privacy-conscious manner, even when domain shifts are encountered.
Xunzheng Zhang   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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