Results 111 to 120 of about 10,992,643 (300)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
STANDARDS OF MECHANICAL FILTRATION PLANT PERFORMANCE
American Journal of Public Health, 1916 The standards suggested in this paper are the result of a study of the operation of filtration plants in Maryland upon which the writer was detailed under the general direction of Mr. R. B. Morse, Chief Engineer, Maryland State Department of Health. Acknowledgment is given here both to him and the writer's brother, Dr.
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
This study investigates the effects of annealing treatment on the residual stress, microstructure, and mechanical properties of 7075 aluminum alloy. Experimental characterization and finite element simulations using ABAQUS/CAE were conducted to assess ...
Tang, Peng +5 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Power Enhancement and Spot Homogenization Design for Arrayed Semiconductor Lasers
MicromachinesImproving the spot brightness and uniformity of arrangement of the array laser is conducive to ensuring the beam quality of the fiber laser. Based on the light tracing principle, the optical model performance of two common fiber lasers was first analyzed.
Shunshun Zhong +4 more
doaj +1 more source
Data-driven modelling of mechanical properties
, 2022 Computational simulation of mechanical structures is an important tool for the design and optimization of structural components and the control of new processes.
Chang, Eldridge Wen Wei
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
MachinesUltra-high-speed cutting (UHSC) has emerged as a transformative manufacturing technology aimed at overcoming the long-standing machining challenges associated with high-performance difficult-to-machine composites (HPDMCs).
Junjie Zou +7 more
doaj +1 more source