Results 151 to 160 of about 7,419,589 (253)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Avignon and Paris sketchbook [picture] /

, 1930
Title devised by cataloguer.; Part of the John Power sketchbooks collection.; Inscriptions: "Avignon + Paris"--In pencil on front cover.; Condition: Yellowing, soiled, stained.; Also available online at: http://nla.gov.au/nla.pic-vn6292743; Exhibited ...
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core  

Ventilation Intensity and Prognosis in Pediatric Oncology: Mechanical Power, Compliance, and Mortality Risk. [PDF]

Pediatr Pulmonol
Camargo BS, Santos GMVD, Araujo OR, Ribeiro CO, Silva DCBD.   +4 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Miscellaneous sketchbook, 2 [picture] /

, 1930
Title devised by cataloguer from acquisitions documentation.; Part of the John Power sketchbooks collection.; Condition: Yellowing, soiled, stained, tears.; Also available online at: http://nla.gov.au/nla.pic-vn6293848; Exhibited: Abstraction-Creation: J.
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core  

Discrepancies between estimated and geometrically derived mechanical power in invasively ventilated patients - insights from a randomized clinical trial. [PDF]

Intensive Care Med Exp
Serafini SC, Geerts JWHJ, Neto AS, List SS, von Düring S, Tschernko E, Bühler P, Mazzinari G, Paulus F, Schultz MJ, Buiteman-Kruizinga LA, INTELLiPOWER collaborative investigators.   +11 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Norfolk sketchbook [picture] /

, 1930
Title devised by cataloguer.; Part of the John Power sketchbooks collection.; Inscriptions: "Norfolk"--In pencil on front cover.; Condition: Yellowing, soiled, stained.; Also available online at: http://nla.gov.au/nla.pic-vn6292751; Exhibited ...
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core  

Mechanical power of ventilation: tracking the damaging component. [PDF]

Crit Care
Marini JJ, Crooke PS, Rocco PRM.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source