Results 1 to 10 of about 11,100 (162)

Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI)

PLoS ONE, 2021
Monocytes and vascular endothelial growth factor (VEGF) have profound effects on tissue injury and repair. In ventilator-induced lung injury (VILI), monocytes, the majority of which are Ly6C+high, and VEGF are known to initiate lung injury.
Chung-Sheng Shi, Chin-Kuo Lin, Tzu Hsiung Huang   +2 more
exaly   +4 more sources

Inhibition of antiapoptotic BCL-2 proteins with Lipo-NPs induces fibroblast apoptosis, alleviating pulmonary fibrosis in VILI mice [PDF]

Respiratory Research
Background Mechanical ventilation in critically ill patients can potentially result in ventilator-induced lung injury (VILI). Additionally, mechanical stretching might activate the pro-fibrotic signaling pathways, which could contribute to programmed ...
Qian Yu, Rui Tang, Wen Tang, Shulei Fan, Daoxin Wang, Junnan Peng   +5 more
doaj   +3 more sources

Ventilator‐Induced Lung Injury: Mechanotransduction and Potential Therapeutic Targets [PDF]

MedComm
Mechanical ventilation (MV) serves as a critical intervention to maintain adequate gas exchange. Unfortunately, MV often leads to the development of ventilator‐induced lung injury (VILI).
He Ren, Ziqi Shang, Alastair G. Stewart, Ying‐xin Qi, Kai Huang   +4 more
doaj   +2 more sources

Determinants of Cervical Cancer Screening Accuracy for Visual Inspection with Acetic Acid (VIA) and Lugol’s Iodine (VILI) Performed by Nurse and Physician

PLoS ONE, 2017
BackgroundVisual inspection with acetic acid (VIA) and Lugol's iodine (VILI) are used to screen women for cervical cancer in low-resource settings. Little is known about correlates of their diagnostic accuracy by healthcare provider.
Eduardo Franco, Mariam El-Zein, Stephen Walter   +2 more
exaly   +3 more sources

Caveolin‐1 Is a Central Mediator of Acute Lung Injury in an Animal Model of Sickle Cell Disease [PDF]

Pulmonary Circulation
Acute chest syndrome in sickle cell disease (SCD) carries high morbidity and mortality, with up to 15% of patients requiring invasive mechanical ventilation.
Clare C. Prohaska, Justin R. Sysol, Nicole Jones, Robert W. Wysocki, Suellen D. Oliveira, Richard D. Minshall, Roberto F. Machado   +6 more
doaj   +2 more sources

Pendrin inhibition is associated with protective effect of prone positioning in a ventilator-induced lung injury mouse model [PDF]

Scientific Reports
Pendrin (SLC26A4), a transmembrane anion exchanger, is upregulated in inflammatory airway diseases. In this study, we analyzed the role of pendrin expression in a ventilator-induced acute lung injury (VILI) animal model. VILI was induced in the supine or
Ji Soo Choi, Mi Hwa Shin, Go Eun Oh, Doo Na Song, Wan NamKung, Gyoon Hee Han, Jae Young Choi, Moo Suk Park   +7 more
doaj   +2 more sources

Electrical Impedance Tomography: the future of mechanical ventilation?

Journal of Mechanical Ventilation, 2021
Electrical Impedance Tomography is a rapidly evolving technology used for bedside lung imaging. Although EIT devices have been commercially available for the past decade, they are still not commonly used in everyday clinical practice.
Melina Simonpietri, Mia Shokry, Ehab G. Daoud   +2 more
doaj   +1 more source

Influence of age, mechanical power, its fragments and components on the mortality rate in SARS-CoV-2 patients undergoing mechanical ventilation

Journal of Mechanical Ventilation, 2022
Introduction The Acute Respiratory Distress Syndrome caused by the Coronavirus 2019 (SARS-CoV-2) may be associated with the Acute Respiratory Distress Syndrome (ARDS) and Ventilation Induced Lung Injury (VILI).
Claudio Luciano Franck, Gustavo Maysonnave Franck, Raquel Galvão   +2 more
doaj   +1 more source

Rutin alleviates ventilator-induced lung injury by inhibiting NLRP3 inflammasome activation

iScience, 2023
Summary: Whether rutin relieves ventilator-induced lung injury (VILI) remains unclear. Here, we used network pharmacology, bioinformatics, and molecular docking to predict the therapeutic targets and potential mechanisms of rutin in the treatment of VILI.
Shengsong Chen, Yu Bai, Jingen Xia, Yi Zhang, Qingyuan Zhan   +4 more
doaj   +1 more source

Unusual paraseptal emphysema as the primary changes in computerized tomography scan of a COVID-19 patient

Journal of Mechanical Ventilation, 2020
Covid-19 pandemic has infected more than 20 million people worldwide and claimed more than 750,000 lives so far. Given that this disease is new, the long-term lung effects for survivors especially of severe cases are unknown.
Dan Bendsten, Takkin Lo
doaj   +1 more source