Results 51 to 60 of about 448,246 (218)

Effect of Morphology and Mechanical Stability of Nanometric Platinum Layer on Nickel Foam for Hydrogen Evolution Reaction

open access: yesEnergies, 2019
Platinum thin films are deposited on open-cell nickel foam with porosity of 95% via spontaneous galvanic displacement. Ni foams with different morphologies and pore size are compared and characterized by electrochemical and structural analysis techniques.
Rachela G. Milazzo   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

First-Principles Investigation of Pressure-Induced Structural, Elastic, and Vibrational Properties of In3Sc

open access: yesCrystals
This study reports a first-principles investigation of the structural, mechanical, electronic, and vibrational properties of In3Sc in several crystal structures: AuCu3 (Pm3¯m), Al3Ti (I4/mmm), Ni3Sn (P63/mmc), and BiF3 (Fm3¯m), with a focus on pressure ...
Yazid Hedjar   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Effect of Geometric Design on the Mechanical Performance of Digital Light Processing (DLP)-Printed Microneedles

open access: yesMicromachines
This study describes the processing of microneedle (MN) arrays with three different heights of arrowhead (600 µm (A1), 800 µm (A2), and 1000 µm (A3)), pyramid (600 µm (P1), 800 µm (P2), and 1000 µm (P3)), and turret (600 µm (T1), 800 µm (T2), and 1000 µm
Tuba Bedir   +4 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Investigation of the Sealing and Mechanical Stability of Cap Rock for Offshore CO2 Sequestration in Saline Aquifers

open access: yesEnergies
Offshore saline aquifer CO2 sequestration relies heavily on the sealing integrity and mechanical stability of mudstone caprocks, yet their responses to supercritical CO2 (scCO2) remain inadequately constrained for marine geological settings.
Jinsen Li   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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