Intracellular Mechanical Stress-Mediated Autophagy Cell Death via Nanospikes for Cancer Treatment. [PDF]
Li Y +11 more
europepmc +1 more source
A computationally efficient thermo-mechanical model with temporal acceleration for prediction of residual stresses and deformations in WAAM [PDF]
Yabin Yang, Haofeng Lin, Quan Li
openalex +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Lung adenocarcinoma cells respond differently to mechanical stress in 3D versus 2D environments. [PDF]
Kitamura N +16 more
europepmc +1 more source
The impact of curculigoside on osteogenic differentiation and orthodontic tooth movement in osteoporosis under mechanical stretch stress [PDF]
Xinyu Liu +4 more
openalex +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Mechanical Stress Reveals Asymmetry of Sodiation and Desodiation of Hard Carbon. [PDF]
Mück S +4 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

