In vivo mechano-tissue engineering by hydrogels capable of transmitting intercellular mechanical stress. [PDF]
Ueda N +10 more
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Elucidating the underlying mechanism of mechanical stress-induced impact on mRNA-LNP structure. [PDF]
Jensen EL +8 more
europepmc +1 more source
Electromagnetic and Mechanical Stress Analysis of a 5 MW High-Pole Non-Overlap Winding Wound-Rotor Synchronous Wind Generator [PDF]
Karen S. Garner, Udochukwu B. Akuru
openalex +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Tissue scaffold architecture affects implant degradation and bone tissue regeneration: A novel in silico mechanobiological model analysing cell behavior, mechanical stress and degradation kinematics. [PDF]
Alshammari A, Alabdah F, Li L, Cooper G.
europepmc +1 more source
Thermal-Mechanical Physics Informed Deep Learning For Fast Prediction of Thermal Stress Evolution in Laser Metal Deposition [PDF]
Resham Sharma, Y. B. Guo
openalex +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Loss of mechanical stress induces synovitis, fibrosis and articular cartilage degeneration via distinct synovial cell subsets. [PDF]
Ishikura H +15 more
europepmc +1 more source

