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Moderate mechanical stress suppresses the IL‐1β‐induced chondrocyte apoptosis by regulating mitochondrial dynamics

Journal of Cellular Physiology, 2021
Mitochondrial dysfunction contributes to osteoarthritis (OA) onset and progress. Mitochondrial dynamics, coupled with mitophagy, is critical for the maintenance of mitochondrial fitness, involving many cellular processes, such as proliferation and ...
Jiaming Zhang   +4 more
semanticscholar   +1 more source

Mechanical stress.

Handbook of Clinical Neurology, 2015
This chapter discusses mechanical stressors that are believed to be associated with work-related musculoskeletal disorders. It starts with an introduction to work-related musculoskeletal disorders (particularly those with high incidences in workplaces, such as disorders of low back, neck/shoulder, hand/wrist, elbow, and knee) in high-risk industries ...
S. Bao
semanticscholar   +4 more sources

Mechanisms of memory under stress

Neuron, 2022
It is well established that stress has a major impact on memory, driven by the concerted action of various stress mediators on the brain. Recent years, however, have seen considerable advances in our understanding of the cellular, neural network, and cognitive mechanisms through which stress alters memory.
Schwabe, Lars   +3 more
openaire   +2 more sources

Investigations of SiC MOSFET Short-Circuit Failure Mechanisms Using Electrical, Thermal, and Mechanical Stress Analyses

IEEE Transactions on Electron Devices, 2020
In this study, unique short-circuit failure mechanisms in 1.2-kV SiC metal–oxide–semiconductor field-effect transistors (MOSFETs) at 400 and 800-V dc bias were investigated using experiments and numerical TCAD simulations, taking electrical, thermal, and
Kailun Yao   +3 more
semanticscholar   +1 more source

The mechanisms of stress and immunosuppression

Medical Hypotheses, 1981
The effects of stress on the central nervous system, endocrine balance and immunity were observed in male Sprague-Dawley rats. Food and water were supplied in unlimited quantities. Extraneous odors were kept away from the control room by an exhaust fan in the adjacent room. At 70 days, experimentation occured for 20 days.
M. Keeling, J. Richardson
openaire   +3 more sources

Stress — mechanisms of immunosuppression

Veterinary Immunology and Immunopathology, 1991
Stress, a term commonly used to describe varied phenomena, should be restricted to describe an adaptive response by an animal to threats to homeostasis. The threats to homeostasis are called stressors. Stressors include a variety of physical, psychological, chemical, or infectious causes that are modified by intrinsic and extrinsic factors. Examples of
John E. Dohms, Alan Metz
openaire   +3 more sources

Rethink Stress Mechanisms

2022
This study has two primary objectives: 1. Compare the durability of two different stress mindset interventions: (a) A meta-cognitive stress mindset intervention that explains that stress can be both positive and negative and that the way people view stress can, in part, determine whether they experience positive or negative effects from it (b) The ...
Handley-Miner, Isaac   +3 more
openaire   +1 more source

On Stress and Coping Mechanisms

Issues in Mental Health Nursing, 1985
(1985). On Stress and Coping Mechanisms. Issues in Mental Health Nursing: Vol. 7, No. 1-4, pp. 3-24.
Hans Selye, Jean Tachè
openaire   +2 more sources

Influence of tectonic stress on coalification: Stress degradation mechanism and stress polycondensation mechanism

Science in China Series D: Earth Sciences, 2007
The function of pressure for coalification is a long-term controversial issue, and the main cause is that the strata pressure and the tectonic stress were confused, which are two different actions of “pressure”. The former benefits the physical coalification but retards the chemical coalification, whereas the latter may not only affect the physical ...
Zhang ShouRen, Cao Daiyong, LI XiaoMing
openaire   +2 more sources

Mechanical Stress Induced Mechanism of Microtubule Catastrophes

Journal of Molecular Biology, 2005
Microtubules assembled in vitro from pure tubulin can switch occasionally from growing to shrinking states or resume assembly, an unusual behavior termed "dynamic instability of microtubule growth". Its origin remains unclear and several models have been proposed, including occasional switching of the microtubules into energetically unfavorable ...
Hunyadi, V.   +2 more
openaire   +3 more sources

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