Results 61 to 70 of about 7,604,628 (414)

Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression

Nature Communications, 2017
The surrounding microenvironment limits tumour expansion, imposing a compressive stress on the tumour, but little is known how pressure propagates inside the tumour.
M. Dolega, M. Delarue, F. Ingremeau, J. Prost, A. Delon, G. Cappello   +5 more
semanticscholar   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury

Frontiers in Molecular Neuroscience, 2019
Mechanical stress and hypoxia during episodes of ocular hypertension (OHT) trigger glial activation and neuroinflammation in the retina. Glial activation and release of pro-inflammatory cytokines TNFα and IL-1β, complement, and other danger factors was ...
Alexey Pronin, Dien Pham, Weijun An, Galina Dvoriantchikova, Galina Reshetnikova, Jianzhong Qiao, Zhanna Kozhekbaeva, Ashlyn E. Reiser, Vladlen Z. Slepak, Valery I. Shestopalov, Valery I. Shestopalov, Valery I. Shestopalov   +11 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Strength Analysis and Design of a Multi-Bridge V-Shaped Rotor for High-Speed Interior Permanent Magnet Synchronous Motors

Actuators
High-speed operation is a crucial approach for achieving high power density of drive motors for new energy vehicles. However, mechanical strength of the rotor has become the primary bottleneck in the development of high-speed drive motors.
Kun Zhou, Dongxiong Wang, Zewen Yu, Xianju Yuan, Ming Zhang, Yu Zheng   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Advanced AlGaAs/GaAs Heterostructures Grown by MOVPE

Crystals, 2019
AlGaAs/GaAs heterostructures are the base of many semiconductor devices. The fabrication of new types of devices demands heterostructures with special features, such as large total thickness (~20 μm), ultrathin layers (~1 nm), high repeatability (up
Maxim A. Ladugin, Irina V. Yarotskaya, Timur A. Bagaev, Konstantin Yu. Telegin, Andrey Yu. Andreev, Ivan I. Zasavitskii, Anatoliy A. Padalitsa, Alexander A. Marmalyuk   +7 more
doaj   +1 more source

MicroRNA-378 suppresses myocardial fibrosis through a paracrine mechanism at the early stage of cardiac hypertrophy following mechanical stress.

Theranostics, 2018
Rationale: Excessive myocardial fibrosis is the main pathological process in the development of cardiac remodeling and heart failure; therefore, it is important to prevent excessive myocardial fibrosis.
Jie Yuan, Haibo Liu, Wei Gao, Li Zhang, Y. Ye, Ling-Yan Yuan, Z. Ding, Jian Wu, Le Kang, Xiaoyi Zhang, Xiaoyan Wang, Guoping Zhang, H. Gong, A. Sun, Xiangdong Yang, Ruizhen Chen, Zhaoqiang Cui, J. Ge, Y. Zou   +18 more
semanticscholar   +1 more source

The Stress Mechanism of Zinc on the Wheat

Chemical Engineering Transactions, 2017
To investigate the stress mechanism of zinc on the wheat, different concentrations of zinc were used to treat wheat, and the ultrastructure of mesophyll cells of wheat was observed by transmission electron microscope (TEM). The results showed that at the tillering stage, the number of chloroplast decreased, and the thylakoid of chloroplast of mesophyll
Su Z., Liang C., Sun Y., Liu X., Song C., Chen J., Sun F., Bao Y., Zhang J.   +8 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source