Results 101 to 110 of about 1,697,500 (308)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Research on Skin Friction Drag Reduction by Vibrant Wall
To reduce aerodynamic drag, reduction of skin friction is required. Vibrant flexible wall has been proposed to reduce skin friction drag for a long time. However, there are many problems for the flexible wall to get practical durability, easy maintenance
Kazuo YANAGIMOTO +3 more
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Thermal behaviour of single ply triaxial woven fabric composites [PDF]
This paper studies the complex thermal deformation of single-ply triaxial weave com- posites. This behaviour is studied experimentally, by testing ?at plates and narrow strips of TWF, and numerically, by carrying out ?nite-element simulations that ...
Kueh, A. B. H., Pellegrino, S.
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Analyzing of nonlinear carrying performance of hydrostatic ram is among key research questions to improve heavy machine tools because the machining precision will be directly influenced by it.
Yumo Wang +5 more
doaj +1 more source
Report of the sensor cooler technology panel [PDF]
The Sensor Cooler Technology Panel identified three major areas in which technology development must be supported in order to meet the system performance requirements for the Astrotech 21 mission set science objectives. They are: long life vibration free
Castles, S. +4 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Fatigue Damage Assessment of Turbine Runner Blades Considering Sediment Wear
The wear phenomenon that occurs on the blades during operation has a significant impact on the fatigue life of the blades. To address the issue of fatigue life assessment for turbine runner blades subjected to increased dynamic stress due to sediment ...
Haifeng Chen +4 more
doaj +1 more source
Testing of ROMPS robot mechanical interfaces and compliant device [PDF]
The Robot Operated Materials Processing System (ROMPS) has been developed at Goddard Space Flight Center (GSFC) under a flight project to investigate commercially promising in-space material processes and to design reflyable robot automated systems to be
Antrazi, Sami S., Nguyen, Charles C.
core +1 more source

