Results 51 to 60 of about 1,697,500 (308)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Study of stress corrosion in aluminum alloys [PDF]

open access: yes, 1967
Mechanism of the stress corrosion cracking of high-strength aluminum alloys was investigated using electrochemical, mechanical, and electron microscopic techniques.
Brummer, S. B.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Hastelloy X properties, data, and metallurgical characteristics [PDF]

open access: yes, 1968
Literature survey and testing program were initiated to obtain pertinent information for Hastelloy X, a nickel-base alloy, through the temperature range of minus 423 degrees to 1800 degrees F.
Glasier, L. F., Jr.
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Torque modeling of a novel magnetic coupler with multi-disk flux regulation via angular displacement: analytical FEM co-design [PDF]

open access: yesMechanical Sciences
This paper proposes a novel axially fixed multi-disk magnetic flux-regulatable magnetic coupler with modular topology, which addresses critical limitations such as the structural scalability of conventional magnetic couplers.
S. Zheng   +5 more
doaj   +1 more source

The processing and testing of aluminium matrix composite wires, double composites and block composites [PDF]

open access: yes, 2006
The Composite Processing and Testing Laboratory operated for about 15 years in USA. After that, in 2004- 2005, it moved from Boston to the Budapest University of Technology and Economics One of the main results from research and development projects is
Dobránszky, János   +3 more
core  

The Planck-LFI flight model composite waveguides [PDF]

open access: yes, 2009
The Low Frequency Instrument on board the PLANCK satellite is designed to give the most accurate map ever of the CMB anisotropy of the whole sky over a broad frequency band spanning 27 to 77 GHz.
A Mennella   +32 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

In situ nanocompression testing of irradiated copper. [PDF]

open access: yes, 2011
Increasing demand for energy and reduction of carbon dioxide emissions has revived interest in nuclear energy. Designing materials for radiation environments necessitates a fundamental understanding of how radiation-induced defects alter mechanical ...
Hosemann, P   +3 more
core   +3 more sources

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