Results 91 to 100 of about 2,381 (165)

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, Volume 13, Issue 16, 18 March 2026.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Clinical study of mild hypothermia therapy after endovascular mechanical thrombectomy for acute anterior circulation massive cerebral infarction

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To explore the efficacy and safety of mild hypothermia therapy in patients with acute anterior circulation massive cerebral infarction after endovascular mechanical thrombectomy.
ZHANG Jia⁃qi, LIU Yang, SHI Yi, REN Zhi⁃qiang, HAN Bing⁃sha, FENG Guang   +5 more
doaj   +1 more source

Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery

Advanced Science, Volume 13, Issue 13, 3 March 2026.
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li, Yunfei Dong, Yaode He, Juanjuan Zheng, Hui Liu, Lu Li, Xiaoxu Hao, Yanli Zhao, Zefeng Yang, Yuankai Sun, Zhiwei Du, Bo Zhao, Weihang Zhou, Honghui Wu, Tianyuan Zhang, Jiahe Wu, Xiangrui Liu, Xianzhen Yin, Zhicai Chen, Rui Xue, Min Lou, Zhen Gu, Xinchi Jiang, Jianqing Gao   +23 more
wiley   +1 more source

Longitudinal plasma interleukin‐6 and post‐stroke cognitive outcomes: The Stroke‐IMPaCT study

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Inflammatory factors, particularly interleukin (IL)‐6, are implicated in post‐stroke cognitive decline, yet the association with longitudinal changes in these markers remains unclear. METHODS Plasma IL‐6 and other inflammatory markers were measured within 96 hours of ischemic stroke, and at 6–9 and 18–21 months, alongside ...
Natasha S. Carmichael, Harry R. Deijnen, Siew Yan Wong, Thomas O. Williams, Evangelos Kontopantelis, Luke Cowie, Eileen Jones, Lauren Drag, Marion S. Buckwalter, John R. Grainger, Stuart M. Allan, Craig J. Smith   +11 more
wiley   +1 more source

Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy

Annals of Neurology, Volume 99, Issue 3, Page 692-704, March 2026.
Objective The first‐pass effect (FPE), defined as excellent reperfusion after a single attempt, is associated with improved outcomes in large vessel occlusion stroke. We evaluated whether intravenous tenecteplase (TNK) compared with alteplase (TPA) increases the likelihood of FPE in basilar artery occlusion (BAO).
Dylan N. Wolman, Rahul R. Karamchandani, Sina Hemmer, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Clemens M. Schirmer, Alexandra R. Paul, Bradley N. Bohnstedt, Raul G. Nogueira, Philipp Hendrix   +38 more
wiley   +1 more source

Application of modified SWIM technique in mechanical thrombectomy of acute ischemic stroke

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the efficacy and safety of modified SWIM technique for mechanical thrombectomy in patients with acute ischemic stroke. Methods Total 114 patients with acute ischemic stroke who underwent mechanical thrombectomy in The Third the ...
CUI Jie⁃men, YE Bin, GONG Xin, ZHANG Hong⁃yan, SUN Xuan   +4 more
doaj   +1 more source

Revisiting Incomplete Tissue‐Level Reperfusion Following Successful Thrombectomy for Acute Ischemic Stroke

Annals of Neurology, Volume 99, Issue 3, Page 668-683, March 2026.
[Color figure can be viewed at www.annalsofneurology.org] Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains ...
Yue Qiao, Adrien Ter Schiphorst, Yi Xu, Jean‐Claude Baron, Wenbo Zhao   +4 more
wiley   +1 more source

National Trends in Cerebrovascular Disease–Related Mortality among Adults With Obesity in the United States, 1999–2020

Brain and Behavior, Volume 16, Issue 3, March 2026.
Using U.S. CDC WONDER mortality data from 1999–2020, cerebrovascular disease–related mortality among adults with obesity increased steadily, with acceleration after 2008. Pronounced disparities were observed by sex, race/ethnicity, geography, and age, with the fastest increases among younger adults.
Ibrahim Nagmeldin Hassan, Siddig Yaqub, Muhsin Ibrahim, Nagmeldin Abuassa, Mohamed Ibrahim, Shahzaib Ahmed, Allahdad Khan, Hamza Ashraf   +7 more
wiley   +1 more source

Treating hemodialysis access thrombosis with the InThrill Thrombectomy System: Technique and case report

Radiology Case Reports
The purpose of this report is to describe via a case example an efficient mechanical thrombectomy technique for hemodialysis access thrombosis using the InThrill Thrombectomy System (Inari Medical, Irvine, CA).
Luke Wright, MD, Dan Schneider, MEd
doaj   +1 more source

Coronary Slow Flow and No‐Reflow During Percutaneous Coronary Intervention: Contemporary Insights Into Imaging‐Guided Prediction, Prevention, and Management

Catheterization and Cardiovascular Interventions, Volume 107, Issue 4, Page 1198-1205, March 1, 2026.
ABSTRACT Coronary slow flow (SF) and no‐reflow (NR) are clinically significant complications of percutaneous coronary intervention (PCI), particularly in ST‐segment elevation myocardial infarction (STEMI) and saphenous vein graft (SVG) interventions. Angiographically defined as impaired myocardial perfusion despite restored epicardial patency, SF/NR ...
Bharat Khialani, Eran Sim, George Touma, Sarah Fairley, Cuneyt Ada, Bernard Wong   +5 more
wiley   +1 more source