Results 91 to 100 of about 2,591,649 (241)

Biomimetic PB@PDA‐CA@Mem nanoplatform regulates oxidative stress and inflammatory microenvironment to enhance stroke recovery

VIEW, EarlyView.
PB@PDA‐CA@Mem enhances ischemic brain accumulation and enables acid‐responsive CA release. Through broad‐spectrum ROS/RNS scavenging, Nrf2/Keap1 activation, and NF‐κB/NLRP3 suppression, it alleviates oxidative stress and neuroinflammation, preserves neuronal architecture, reduces infarction, and improves functional recovery.
Lei Shi, Zhuonan Wang, Chenxi Zhou, Shuping Wang, Xuting Shen, Si Cheng, Yongli Yang, Nengrui Guo, Zhengrong Zhong, Lijun Bai   +9 more
wiley   +1 more source

Mechanical Thrombectomy for M2 Occlusions: A Single-Centre Experience

, 2017
<b><i>Background:</i></b> The recent success of several mechanical thrombectomy trials has resulted in a significant change in the management of patients presenting with stroke.
Marta Aguilar Pérez, Oliver Ganslandt, Hans Henkes, Philipp Bücke, Hansjörg Bäzner, Pervinder Bhogal   +5 more
core   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Histological analysis of thrombus composition in acute ischemic stroke with large vessel occlusion: impact of r-tPA treatment

Frontiers in Neuroscience
Background and purposeMechanical thrombectomy advances enable detection of thrombus composition changes post-intravenous thrombolysis, but evidence remains limited.
Changzhi Zhao, Guofang Chen, Zhiliang Guo, Sha Chen, Lei Ping, Qiao Li, Xiaoying Zhang, Manhua Ding, Yang Zhang, Yang Zhang   +9 more
doaj   +1 more source

Pulmonary Embolism—A Century of Progress

ANZ Journal of Surgery, EarlyView.
Reviews a century of progress in the diagnosis, prevention, and management of pulmonary embolism; from the first successful surgical embolectomy in 1924 to advanced imaging, pharmacological thromboprophylaxis, and treatment. In the 21st century, advances include catheter‐directed thrombolysis or mechanical thrombectomy under decision‐making guidance of
D. A. Watters
wiley   +1 more source

Diagnosis of acute ischemia using dual energy CT after mechanical thrombectomy

, 2016
To assess the performance of dual energy unenhanced CT in the detection of acute ischemia after mechanical ...
Courvoisier, Delphine, Vargas Gomez, Maria Isabel, Krauss, Bernhard, Mendes Pereira, Vitor, Sztajzel, Roman, Gariani, Joanna, Cuvinciuc, Victor, Lövblad, Karl-Olof, Mendes Pereira V, Sztajzel R, Vargas MI, Lovblad KO, Courvoisier D, Krauss B, Cuvinciuc V, Gariani J   +15 more
core   +1 more source

Highly potent, brain‐penetrant EP2 receptor antagonists for the treatment of permanent focal cerebral ischaemia in male and female mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Cerebral ischaemia is a leading cause of death in older adults and imposes a substantial global economic burden. Recent studies indicate that inhibiting the Gαs‐coupled EP2 receptor reduces ischaemic brain injury by modulating neuroinflammation.
Zhen Jin, Chenyao Jiang, Eun Bee Cho, M. Dennis Leo, Jiukuan Hao, Jiawang Liu, Ying Yu, Jianxiong Jiang   +7 more
wiley   +1 more source

Effect of mechanical thrombectomy alone or in combination with intravenous thrombolysis for acute ischemic stroke

, 2018
Whether combining intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) is superior to mechanical thrombectomy alone for large vessel occlusion acute ischemic stroke is still uncertain.
Konda, Daniel, Diomedi, Marina, Morosetti, Daniele, Koch, Giacomo, Koch G., Gandini, Roberto, Gandini R., Sallustio F., Konda D., Fabiano S., Sallustio, Fabrizio, Diomedi M., Pampana E., Alemseged F., Fabiano, Sebastiano, Alemseged, Fana, Pampana, Enrico   +16 more
core   +1 more source

Recurrent Cardioembolic Stroke Treated Successfully with Repeated Mechanical Thrombectomy within the Acute Index Stroke Period [PDF]

, 2015
BACKGROUND: The safety of repeated mechanical thrombectomy within the acute stroke period has not yet been clearly demonstrated. We describe herein a patient who was successfully treated with repeated mechanical thrombectomy within the acute index stroke
김병문, 김동준, 김세훈, 김영대, 이윤주, 남효석, 허지회   +6 more
core   +1 more source

Utility of the SWAM (Separator With Aspirator for Mechanical Thrombectomy) Device in Managing Hemodialysis Access Thrombosis

Hemodialysis International, EarlyView.
ABSTRACT Background Hemodialysis access thrombosis is the primary cause of access failure. Thrombus removal is an effective strategy to restore access function. Although both open surgical and endovascular procedures enable thrombus clearance, endovascular thrombus reduction therapy is widely adopted in clinical practice for this condition due to its ...
Lin Li, Zhongwang Zhang, Hongjie Wang, Mingdi Zhu, Kun Wang, Zheng Liu   +5 more
wiley   +1 more source