Results 61 to 70 of about 2,429,653 (258)

Data of mechanical thrombectomy with Solitaire.

, 2016
Data of mechanical thrombectomy with Solitaire.
Jun Zhang (48506), You-ran Lu (2199511), Shaowei Jiang (2199505), Shuming Pan (2199508), Aihua Fei (2199502), Ya Peng (450850), Hai-rong Wang (2199514), Miao Chen (213356)   +7 more
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Paradoxical pulmonary artery systolic pressure response with catheter-directed therapies for pulmonary embolism

American Heart Journal Plus, 2023
Background: Early data on use of catheter-directed therapies (CDT) for treatment of Intermediate or High-Risk pulmonary embolism (PE) show improvement in pulmonary artery systolic pressures (PAsP) and RV/LV ratios. Occasionally a paradoxical rise in PAsP
Patrick Ho, Farouk Al-Chami, Mara Caroline, Eric Gnall, Joseph Bonn, Lee Greenspon   +5 more
doaj   +1 more source

A Case of Comorbid Weber Syndrome Following Mechanical Thrombectomy for Middle Cerebral Artery Occlusion

, 2023
Xiao-Bing Li, Hao Feng, Yi Dai, Wei Liu Department of Neurology, Beijing Haidian Hospital, Beijing, 100730, People’s Republic of ChinaCorrespondence: Wei Liu; Yi Dai, Department of Neurology, Beijing Haidian Hospital, No.
Li XB, Feng H, Dai Y, Liu W
core  

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

The Effectiveness and Safety of Mechanical Thrombectomy Compared with Thrombolytic Therapy in Acute Stroke: A Systematic Review and Meta-Analysis

Health Technology Assessment in Action, 2017
Background: This study aims to investigate the effectiveness of mechanical thrombectomy compared with thrombolytic therapy in patients with acute stroke.
Mojtaba Nouhi, Reza Jahangiri, Saber Azami, Mehrshad Azizi, Saman Ghasempour, Abdoreza Mousavi   +5 more
doaj   +1 more source

Update on Mechanical Thrombectomy [PDF]

Journal of Neurology & Neurophysiology, 2015
Intra-arterial stroke therapy aims to restore perfusion of the distal arterial bed by recanalizing the primary arterial occlusive lesion [1]. Successful recanalization positively correlates with improved longterm functional outcomes [2-4]. The PROACT II4 trial published in 1999 demonstrated a clear benefit from administering prourokinase via a catheter-
openaire   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

High White Blood Cell Count Is a Risk Factor for Contrast-Induced Nephropathy following Mechanical Thrombectomy for Acute Ischemic Stroke

Cerebrovascular Diseases Extra, 2020
Background: Although mechanical thrombectomy is a standard endovascular therapy for patients with acute ischemic stroke (AIS), the incidence of and risk factors for contrast-induced nephropathy (CIN) following mechanical thrombectomy are infrequently ...
Yuki Yamamoto, Nobuaki Yamamoto, Yasuhisa Kanematsu, Kazutaka Kuroda, Izumi Yamaguchi, Takeshi Miyamoto, Shu Sogabe, Kenji Shimada, Yasushi Takagi, Yuishin Izumi   +9 more
doaj   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source