Results 121 to 130 of about 2,602,339 (340)

“Time Is Brain” – for Cell Therapies

Advanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source

Endovascular Therapy for Acute Stroke [PDF]

, 2017
Stroke is the most common cause of permanent disability, the second most common cause of dementia, and the fourth most common cause of death in the Western world.
Grunwald, Iris Q., Kastrup, Andreas, Marmagkiolis, Konstantinos, Papanagiotou, Panagiotis, Politi, Maria   +4 more
core   +1 more source

ENDOVASCULAR TREATMENT FOR DISORDERS OF THE VENOUS SYSTEM

Alʹmanah Kliničeskoj Mediciny, 2016
The annual rate of deep vein thrombosis in general population is from 5 to 9 cases per 10 000, whereas for venous thromboembolism (deep vein thrombosis and pulmonary embolism taken together) amounts to 14 cases per 10 000.
A. G. Osiev, M. V. Vishnyakova, B. B. Gegenava   +2 more
doaj   +1 more source

All Nanozyme‐Based Cascade Reactions for Biomedical Applications: from Self‐Cascading Nanozyme to Immobilized Cascade Nanozyme

Advanced Science, EarlyView.
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu, Congcong Jiang, Hian Kee Lee, Yuanjian Zhang, Sheng Tang   +4 more
wiley   +1 more source

Microbubble Cavitation Imaging [PDF]

, 2013
Ultrasound cavitation of microbubble contrast agents has a potential for therapeutic applications such as sonothrombolysis (STL) in acute ischemic stroke.
Everbach, E. Carr, Gao, S. J., Liu, J. J., Porter, T. R., Powers, J. E., Shi, W. T., Vignon, F., Xie, F.   +7 more
core   +3 more sources

In a hub-and-spoke network, spoke-administered thrombolysis reduces mechanical thrombectomy procedure time and number of passes [PDF]

, 2022
Andrew W. Kraft, Amine Awad, Joseph Rosenthal, Adam A. Dmytriw, Justin E. Vranic, Anna K. Bonkhoff, Martin Bretzner, Joshua A Hirsch, James D. Rabinov, Christopher J. Stapleton, Lee H. Schwamm, Natalia S. Rost, Thabele M Leslie‐Mazwi, Aman B. Patel, Robert W. Regenhardt   +14 more
openalex   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Revolution in acute ischaemic stroke care: a practical guide to mechanical thrombectomy [PDF]

, 2017
Rapid, safe and effective arterial recanalisation to restore blood flow and improve functional outcome remains the primary goal of hyperacute ischaemic stroke management.
Cowley, P, Evans, MRB, Werring, DJ, White, P   +3 more
core   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Recanalization and reperfusion in acute ischemic stroke. [PDF]

, 2010
Revascularization remains the most intuitive strategy to reverse ischemic injury associated with arterial occlusion in acute stroke. Revascularization may lead to opening of an occluded artery, or recanalization, yet restoration of downstream flow, or ...
Liebeskind, David S
core   +2 more sources