Results 161 to 170 of about 2,602,339 (340)

Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani, Chee Wee Tan, Deborah M. Siegal   +2 more
wiley   +1 more source

Bilateral dynamic cerebral autoregulation assessment during endovascular treatment in large‐vessel occlusion stroke

Experimental Physiology, EarlyView.
Abstract Recanalization by endovascular treatment (EVT) is effective in acute ischaemic stroke caused by large‐vessel occlusion. Better understanding of the pathophysiology could possibly identify targets for improving peri‐procedural management and thereby patient outcome.
Adam Vittrup Heiberg, Troels Gil Lukassen, Thomas Clement Truelsen, Henrik Gutte Borgwardt, Goetz Benndorf, Christine Sølling, Henrik Winther Schytz, Klaus Hansen, Kirsten Møller, Helle Klingenberg Iversen   +9 more
wiley   +1 more source

The Correlations of Clinical Outcomes and Vascular Morphology With Infarct Patterns in Middle Cerebral Arterial Occlusion

Brain and Behavior, Volume 16, Issue 2, February 2026.
For stroke caused by large vessel occlusion in M1 segment of middle cerebral artery (MCA), a tortuous and long M1 segment of contralateral MCA (cMCA) correlates with the onset of borderzone infarct. In those with a less tortuous cMCA‐M1 segment, a thin and short M1 segment correlates with large infarct.
ZhiRong Cai, Yuan Chen, ShaoQing Pei, Yue He, YaNan Zhu, Rui Zhang, JingWei Lin, Yi Yang, Ying Zhu   +8 more
wiley   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Reduced Frequency of Prolonged Sporadic Hemiplegic Migraine Attacks Following Fremanezumab Treatment—A Case Report

European Journal of Neurology, Volume 33, Issue 2, February 2026.
A 64‐year‐old man was admitted to the stroke unit with acute aphasia and right‐sided hemiplegia, but imaging showed no signs of acute stroke. Symptoms gradually improved and fully resolved by Day 21, following the onset of a hemicranial headache. A diagnosis of sporadic hemiplegic migraine was made, and no further attacks occurred under fremanezumab ...
Julian Frederic Hotz, Lisa Kaindl, Stefan Krebs, Marion Vigl, Julia Ferrari, Christian Neumann, Robert Han, Lavinia Ritscher, Marek Sykora, Paolo Gallmetzer   +9 more
wiley   +1 more source

Construction and application of high‐quality development model for public hospitals oriented to regional medical center: an integrated advanced imaging platform for computed tomography, magnetic resonance imaging, and positron emission tomography‐computed tomography services

Journal of Applied Clinical Medical Physics, Volume 27, Issue 1, January 2026.
Abstract Background The construction of regional medical centers represents a strategic initiative for improving healthcare quality and accessibility in public hospitals. Advanced imaging platforms integrating computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography‐computed tomography (PET‐CT) technologies are ...
Yun Zhang, Sheng‐Li Cheng, Juan Xu, Bao‐Yun Nan, Huan‐Hao Zhou   +4 more
wiley   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo, Yue Wang, Yong Ni, Bin Bo, Jinzhi He, Yongming Zhu, Aiping Qin, Xianyong Zhou, Huaping Du, Yuan Liu, Tianyao Wang, Yudu Li, Yibo Zhao, Zengai Chen, Zhipei Liang, Yao Li, Yuan Xu, Huiling Zhang   +17 more
wiley   +1 more source

Acute Stroke: Present and Future of Catheter-Based Interventions [PDF]

, 2018
: Acute ischemic stroke is a major cause of morbidity and mortality in industrialized nations. The sequel of stroke ranges from mild to severe disability and even death. Since the impairment may be permanent, the costs to society from work incapacity and
Arnold, Marcel, Brekenfeld, Caspar, Gralla, Jan, Schroth, Gerhard   +3 more
core  

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu, Bin Gao, Hongyi Huang, Zesheng Li, Yibin Zhang, Quanlei Liu, Chao Zhang, Yang Dai, Jinkun Xu, Mingshan Liu, Yuanyuan Zhang, Yihe Wang, Penghu Wei, Yuanxiang Lin, Yongzhi Shan, Yumin Luo, Dezhi Kang, Guoguang Zhao   +17 more
wiley   +1 more source