Results 61 to 70 of about 80,331 (298)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Ventilator associated pneumonia in major paediatric burns [PDF]

open access: yes, 2013
Includes abstract.
Rogers, Alan David
core  

Potentially beneficial patient-ventilator dyssynchrony: is it possible? [PDF]

open access: yes
Patient-ventilator dyssynchronies are entities commonly observed during mechanical ventilation. Their persistence can be injurious to lung tissue and the diaphragm.
Adrián Gallardo   +3 more
core   +1 more source

Alveolar mechanics: A new concept in respiratory monitoring

open access: yesJournal of Mechanical Ventilation, 2022
A detailed understanding of respiratory mechanics during mechanical ventilation aids diagnostic accuracy and facilitates close monitoring of patient progress, allowing individualized ventilator adjustments aimed at minimizing ventilator induced lung ...
Ehab G. Daoud, Claudio Luciano Franck
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Comparative Study of the Success Rate of Mechanical Ventilator Liberation between Applying and not Applying Rapid Shallow Breathing Index (RSBI) in Patients with Acute Respiratory Failure after Passing Clinical Readiness Assessment

open access: yesJournal of Health Science and Medical Research (JHSMR), 2016
Objective: To compare the success rate of mechanical ventilator liberation between the application of rapid shallow breathing index (RBSI) and no RSBI application in patient with acute respiratory failure who passed the clinical readiness assessment for ...
Rungsun Bhurayanontachai   +1 more
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Outcomes After Tracheostomy for Patients With Respiratory Failure due to COVID-19

open access: yesEar, Nose & Throat Journal, 2022
Objective: To evaluate the utility and safety of tracheostomy for patients with respiratory failure from COIVD-19 and describe patient clinical characteristics and process of management.
John J. Cardasis MD   +4 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

An Adaptive Neuro-Fuzzy Control of Pneumatic Mechanical Ventilator [PDF]

open access: yes, 2021
COVID-19 was first identified in December 2019 in Wuhan, China. It mainly affects the respiratory system and can lead to the death of the patient. The motivation for this study was the current pandemic situation and general deficiency of emergency ...
Peter Marcinko   +7 more
core   +1 more source

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