Results 161 to 170 of about 14,521 (283)

Single‐Cell Immune Profiling Reveals Neutrophils Promote Myasthenia Gravis Exacerbation Through BAFF Secretion

Advanced Science, EarlyView.
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang, Jingya Dong, Mengyuan Qiu, Jie Bai, Xufeng Cheng, Xiaodong Song   +5 more
wiley   +1 more source

The rapid shallow breathing index as a predictor of successful mechanical ventilation weaning: clinical utility when calculated from ventilator data [PDF]

, 2016
Luiz Alberto Forgiarini, António M. Esquinas   +1 more
openalex   +1 more source

GDF15 Ameliorates Deoxynivalenol‐Induced Anemia by Resolving Ribosomal Stress–Mediated Erythropoietic Arrest

Advanced Science, EarlyView.
Deoxynivalenol induces anemia by disrupting hematopoietic homeostasis and impairing erythroid lineage commitment and differentiation via ribosomal stress–mediated G1/S cell cycle arrest. GDF15 supplementation alleviates this arrest through the β‐catenin–Myc–p21 signaling axis, highlighting GDF15 as a potential therapeutic target for DON‐induced ...
Yan Li, Peijun Jia, Jingxin Zhang, Huan Zhang, Bing Li, Jiawei Chang, Yating Li, Longzhen Zhao, Yazhe Zhen, Tingting Zheng, Yuanlin Xu, Xiuli An, Shijie Zhang   +12 more
wiley   +1 more source

A New Model of Air-Oxygen Blender for Mechanical Ventilators Using Dynamic Pressure Sensors. [PDF]

Sensors (Basel)
Soares GF, Fernandes G, Almeida OM, Lima GD, Rodrigues JJPC.   +4 more
europepmc   +1 more source

Hardware in Mechanical Ventilator : Mechanics of Ventilator

JAPANES JOURNAL OF MEDICAL INSTRUMENTATION, 1983
openaire   +2 more sources

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning, Jie Wang, Yihui Zhang, Hongrui Li, Zenan Jiang, Xinyu Su, Xiao Yang, Xiaoxuan Wu, Bing Wei, Jianmin Ying, Jian Yan, Wenbin Li   +11 more
wiley   +1 more source

Patient–ventilator asynchrony during conventional mechanical ventilation in children [PDF]

, 2017
Guillaume Mortamet, Alexandrine Larouche, Laurence Ducharme‐Crevier, Olivier Fléchelles, Gabrielle Constantin, Sandrine Essouri, Amélie-Ann Pellerin-Leblanc, Jennifer Beck, Christer A. Sinderby, Philippe Jouvet, Guillaume Émériaud   +10 more
openalex   +1 more source

Increasing ventilator surge capacity in COVID 19 pandemic: design, manufacture and in vitro–in vivo testing in anaesthetized healthy pigs of a rapid prototyped mechanical ventilator [PDF]

, 2020
Jayesh Dhanani, George Pang, Jason Pincus, Benjamin J. Ahern, Wendy Goodwin, Nicholas Cowling, Grant Whitten, Mohd H. Abdul‐Aziz, Steven J. Martin, Peter Corke, Kevin B. Laupland   +10 more
openalex   +1 more source

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source