Results 171 to 180 of about 2,495,171 (363)
Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu+17 more
wiley +1 more source
Mechanical ventilation in children
OBJECTIVE: To make a brief review about mechanical ventilation in Pediatrics.METHODS: Review of the classification of types of mechanical ventilation, characteristics of pression and flow waves and indications for its installation. In a sequential way we discuss the various modes of ventilation (control ventilation, assisted-control ventilation ...
openaire +3 more sources
Effect of continuous aspiration of subglottic secretions on the prevention of ventilator-associated pneumonia in mechanically ventilated patients [PDF]
Yang Chen, Haibo Qiu, Yueyong Zhu
openalex +1 more source
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee+5 more
wiley +1 more source
Tracheostomy decannulation leaves an iatrogenic passage in the upper airways. Inadequate sealing leads to pulmonary dysfunction and reduced voice quality. This study aimed to investigate the feasibility and impact of intratracheal tracheostomy sealing on
Rasmus Ellerup Kraghede+6 more
doaj +1 more source
Characterization of Natural Ventilation Systems in Residential Buildings in Portugal - The Importance of Standardization [PDF]
The technical recommendations regarding ventilation in various countries propose average rates of one hourly renewal in main rooms (bedrooms and living/dining rooms) and four renewals per hour in service rooms (kitchens and bathrooms).
Freitas, Vasco, Pinto, Manuel
core
Gastroesophageal reflux in mechanically ventilated pediatric patients and its relation to ventilator-associated pneumonia [PDF]
Tarek A Abdel-Gawad+3 more
openalex +1 more source
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang+8 more
wiley +1 more source
Recollections of My Research in Developing the Heart-Lung Machine at Jefferson Medical College [PDF]
A personal memoir written by Dr. Bernard J. Miller about his introduction to and interest in medical research as well as his experiences working on the heart-lung machine. He focuses specifically on his working relationship with John H.
Miller, Bernard J.
core +1 more source
Home mechanical ventilators: the point of view of the patients [PDF]
Cristina Senent+5 more
openalex +1 more source