Results 41 to 50 of about 516,257 (296)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Heat Transfer Calculations in Barrel Cover of 35 mm Naval Armament System Gun [PDF]
Problemy Mechatroniki, 2018 This paper presents the results of numerical simulations of non-stationary heat transfer in a 35 mm anti-air gun barrel cover made of composite materials. The cover protects the gun against weather conditions, including sea water effects, and serves as a
Zbigniew LECIEJEWSKI +5 more
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Understanding the mechanisms of lung mechanical stress [PDF]
Brazilian Journal of Medical and Biological Research, 2006 Physical forces affect both the function and phenotype of cells in the lung. Bronchial, alveolar, and other parenchymal cells, as well as fibroblasts and macrophages, are normally subjected to a variety of passive and active mechanical forces associated with lung inflation and vascular perfusion as a result of the dynamic nature of lung function. These
Garcia, C. S. N. B. +5 more
openaire +7 more sources
Vibrations and Stability of a Plate in Supersonic Flow Subjected to a Follower Force, and Having a Hinged External Support and a Resilient Attenuation Internal Support [PDF]
Problemy Mechatroniki, 2018 The vibrations and stability of a plate having a finite length were considered in a flat supersonic flow, having adopted an assumption that one of the edges of the plate has a hinged support, and the other edge is free.
Idzi NOWOTARSKI
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Tests of Influence of Selected Gas Operated Weapon’s Action Parameters on its Ballistic and Kinematic Characteristics Part I – Examples of the Results of Theoretical Research [PDF]
Problemy Mechatroniki, 2015 Some results of theoretical tests on influence of selected weapon’s action parameters on ballistic and kinematic characteristics of gas operated short stroke piston weapon are presented in this paper.
Józef GACEK, Grzegorz LEŚNIK
doaj +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Zebrafish epiboly: mechanics and mechanisms
The International Journal of Developmental Biology, 2010 Gastrulation involves of a series of coordinated cell movements to organize the germ layers and establish the major body axes of the embryo. One gastrulation movement is epiboly, which involves the thinning and spreading of a multilayered cell sheet. Epiboly plays a prominent role in zebrafish gastrulation and studies of zebrafish epiboly have provided
Stephanie E. Lepage, Ashley E.E. Bruce
openaire +3 more sources
Reliability Analysis of Ventube Fan Rotor [PDF]
Problemy Mechatroniki, 2015 Discs of ventube fan rotor were chosen as an object of the study. As a result of an analytical calculation, distribution of radial and circumferential stress and safety factor along rotor’s disc radius was calculated.
Stanisław WRZESIEŃ, Michał JASZTAL
doaj +1 more source