Results 51 to 60 of about 410,186 (268)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Cellulose Biomaterials for Tissue Engineering
Frontiers in Bioengineering and Biotechnology, 2019 In this review, we highlight the importance of nanostructure of cellulose-based biomaterials to allow cellular adhesion, the contribution of nanostructure to macroscale mechanical properties, and several key applications of these materials for ...
Ryan J. Hickey +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Mechanism Design with Aftermarkets: Cutoff Mechanisms [PDF]
SSRN Electronic Journal, 2016 I study a mechanism design problem in which a designer allocates a single good to one of several agents, and the mechanism is followed by an aftermarket—a post‐mechanism game played between the agent who acquired the good and third‐party market participants.
openaire +2 more sources
Journal of Economic Theory, 2020 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mackenzie, Andrew, Zhou, Yu
openaire +4 more sources
Compressive Response of Non-slender Octet Carbon Microlattices
Frontiers in Materials, 2019 Lattices are periodic three-dimensional architected solids designed at the micro and nano-scale to achieve unique properties not attainable by their constituent materials.
Akira Kudo +3 more
doaj +1 more source
On the link between mechanics and thermal properties: mechanothermics
New Journal of Physics, 2023 We report on the theoretical derivation of macroscopic thermal properties (specific heat, thermal conductivity) of an electrically insulating rod connected to two reservoirs, from the linear superposition of its mechanical mode Brownian motions.
Eddy Collin +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source