Results 51 to 60 of about 2,666,646 (329)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Job Opening for Nucleosome Mechanic: Flexibility Required

open access: yesCells, 2020
The nucleus has been studied for well over 100 years, and chromatin has been the intense focus of experiments for decades. In this review, we focus on an understudied aspect of chromatin biology, namely the chromatin fiber polymer’s mechanical ...
Mary Pitman   +2 more
doaj   +1 more source

Decoupling of Mechanical and Transport Properties in Organogels via Solvent Variation

open access: yesGels, 2021
Organogels have recently been considered as materials for transdermal drug delivery media, wherein their transport and mechanical properties are among the most important considerations. Transport through organogels has only recently been investigated and
Kenneth P. Mineart   +2 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Impact of Arduino Based STEM Education on Cognitive Domain Level of Mechanics and Scientific Creativity

open access: yesLUMAT
The aim of this study is to investigate the impacts of Arduino-based STEM education on cognitive domain level of mechanics and scientific creativity regarding mechanics, specifically on vectors, kinematics, dynamics and work-energy sub-topics ...
Atakan Coban, Mustafa Erol
doaj   +1 more source

Gauging Newton's Law

open access: yes, 2003
We derive both Lagrangian and Hamiltonian mechanics as gauge theories of Newtonian mechanics. Systematic development of the distinct symmetries of dynamics and measurement suggest that gauge theory may be motivated as a reconciliation of dynamics with ...
Anderson   +7 more
core   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Quantum Mechanics and Stochastic Mechanics for compatible observables at different times

open access: yes, 2001
Bohm Mechanics and Nelson Stochastic Mechanics are confronted with Quantum Mechanics in presence of non-interacting subsystems. In both cases, it is shown that correlations at different times of compatible position observables on stationary states agree ...
Correggi, M., Morchio, G.
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Eurocodes for bridge design versus mechanics

open access: yesBudownictwo i Architektura, 2013
Regulations on which designers base their process of designing of any engineer structures should  include and combine mechanics, loads and dimensioning. It is not always the case as far as eurocodes are concerned.
Sławomir Karaś, Wioleta Czubacka
doaj   +1 more source

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