Results 71 to 80 of about 2,248,361 (334)
Properties of welded joints made in high strength steel using laser technology [PDF]
The usage of high strength steels (HSS) provides numerous benefits in the form of the cross- section area reduction causing weight decrease, improvement in exploitation parameters and in result positive financial effect. The most advantageous results are
Tomasz Ślęzak, Lucjan Śnieżek
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Myofibril based mechanical studies allow evaluation of sarcomeric protein function. We describe a novel method of obtaining myofibrils from primary cardiomyocyte culture.
Kathleen C. Woulfe +10 more
doaj +1 more source
Actin bundle architecture and mechanics regulate myosin II force generation [PDF]
Kimberly L. Weirich +3 more
openalex +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Spatiotemporal patterns of contact across the rat vibrissal array during exploratory behavior
The rat vibrissal system is an important model for the study of somatosensation, but the small size and rapid speed of the vibrissae have precluded measuring precise vibrissal-object contact sequences during behavior.
Jennifer Anne Hobbs +2 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Computer Simulations in Mechanics at the Secondary School
Computer simulations seem to be one of the most effective ways to use computers in physics education. They encourage students to carry out the processes used in physics research: to question, predict, hypothesise, observe, interpret results etc.
Stanislav HOLEC +2 more
doaj +1 more source
The mechanics of mechanical ventilation
The Ventilator has represented an advance in the respiratory support for patients on anesthesia and intensive care. The ventilatory support increases the chance of survival in patients with respiratory failure, and / or major surgical procedures. This paper consists of a summary of advances in the ventilatory support, in describing the physiological ...
Aline Siqueira Melo +2 more
openaire +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

