Results 81 to 90 of about 516,257 (296)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
A Dataset for Mechanical Mechanisms
This study introduces a dataset consisting of approximately 9,000 images of mechanical mechanisms and their corresponding descriptions, aimed at supporting research in mechanism design. The dataset consists of a diverse collection of 2D and 3D sketches, meticulously curated to ensure relevance and quality. We demonstrate the application of this dataset
Ghezelbash, Farshid +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Механика машин, механизмов и материалов, 2016 An article continues the first part published in the previous issue. The first part includes a cause analysis of lowering competitiveness domestic machine building production and the general scheme of creation innovative technically complicated items ...
Vladimir B. Algin
doaj
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Engineering ReportsIn contrast to single‐phase materials the manufacturing process of composites creates multiscale interfaces among constituent materials and between laminar multilayers.
Xiangdong Xue, Mark Robinson, Wei Zhang
doaj +1 more source
LUMATThe aim of this study is to investigate the impacts of Arduino-based STEM education on cognitive domain level of mechanics and scientific creativity regarding mechanics, specifically on vectors, kinematics, dynamics and work-energy sub-topics ...
Atakan Coban, Mustafa Erol
doaj +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source