Results 101 to 110 of about 275,739 (300)

Fracture mechanics of volcanic eruptions [PDF]

, 2009
Seismology is a key tool in the forecasting of volcanic eruptions. The onset of an eruption is often preceded and accompanied by an increase in local seismic activity, driven by fracturing within the edifice.
Matthews, C., Matthews, C
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

20th Australasian Conference on the Mechanics of Structures and Materials (ACMSM20)

, 2009
Futures in Mechanics of Structures and Materials is a collection of peer-reviewed papers presented at the 20th Australasian Conference on the Mechanics of Structures and Materials (ACMSM20, University of Southern Queensland, Toowoomba, Queensland ...
Aravinthan, Thiru, Karunasena, Warna (Karu), Wang, Hao   +2 more
core  

Simulation of the interactions between hydraulic and natural fractures using a fracture mechanics approach

, 2019
HYDROCK method aims to store thermal energy in the rock mass using hydraulically propagated fracture planes. The hydraulic fractures can interact with the pre-existing natural fractures resulting in a complex fracture network, which can influence the ...
Mateusz Janiszewski, Baotang Shen, Mikael Rinne, Rinne, Mikael, Janiszewski, Mateusz, Shen, Baotang   +5 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

On the mechanics of buckling-delamination in compliant laminates [PDF]

, 2009
Many modern electronic devices consist of multilayered stacks of functional materials with a wide range of mechanical properties. Under the influence of thermo-mechanical loading, some of these layers may experience a significant amount of compressive ...
Kleijne, E.D., Bouten, P.C.P., Peerlings, R.H.J., Veenendaal, van, E.   +3 more
core  

Line-tension model for plasticity as the Gamma-limit of a nonlinear dislocation energy [PDF]

, 2012
In this paper we rigorously derive a line-tension model for plasticity as the Gamma-limit of a nonlinear mesoscopic dislocation energy, without resorting to the introduction of an ad hoc cut-off radius.
Scardia, L., Zeppieri, C.I., Zeppieri, C., Zeppieri, CI, Scardia, L Lucia   +4 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Galvanically induced potentials to enable minimal tribochemical wear of stainless steel lubricated with sodium chloride and ionic liquid aqueous solution

Friction, 2018
The effect of galvanically induced potentials on the friction and wear behavior of a 1RK91 stainless steel regarding to tribocorrosion was investigated using an oscillating ball-on-disk tribometer equipped with an electrochemical cell.
Tobias Amann, Felix Gatti, Natalie Oberle, Andreas Kailer, Jürgen Rühe   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source