Results 81 to 90 of about 955,420 (292)

Structural mechanics of deformation and fracture Quarterly progress report [PDF]

open access: yes
Structural mechanics of deformation and fracture - responses of model viscoelastic materials to ...
Gruntfest, I. J., Mueller, G. E.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Preface to the special issue on mechanics of materials. [PDF]

open access: yesInt J Adv Eng Sci Appl Math, 2021
Annabattula RK, Korimilli EP, Datla NV.
europepmc   +1 more source

Measuring strain at the atomic-scale with Differential X-ray Absorption Spectroscopy [PDF]

open access: yes, 2009
Strain-inducing phenomena, such as magnetostriction, lie at the heart of transducer technologies. Knowledge of their origin and mechanics, and how they manifest themselves in different materials, underpins the development and optimisation of sensor and ...
Pascarelli, S, Ruffoni, MP
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

On 3-D inelastic analysis methods for hot section components (base program) [PDF]

open access: yes
A 3-D Inelastic Analysis Method program is described. This program consists of a series of new computer codes embodying a progression of mathematical models (mechanics of materials, special finite element, boundary element) for streamlined analysis of ...
Bak, M. J.   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Comparative Study of Two Aging Treatments on Microstructure and Mechanical Properties of an Ultra-Fine Grained Mg-10Y-6Gd-1.5Zn-0.5Zr Alloy

open access: yesMetals, 2018
Developing high strength and high ductility magnesium alloys is an important issue for weight-reduction applications. In this work, we explored the feasibility of manipulating nanosized precipitates on LPSO-contained (long period stacking ordered phase ...
Huan Liu   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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