Results 61 to 70 of about 955,420 (292)

IMPROVING THE STUDENTS’ LEARNING ACHIEVEMENT ON FLUID MECHANICS COURSE THROUGH THE USE OF INTERACTIVE MEDIA [PDF]

open access: yes, 2009
This research aims at improving the quality of teaching and learning process in Fluid Mechanics course through the use of teaching media. The teaching of Fluid Mechanics needs communicative and authentic media.
Purwantoro, Didik
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Grain Refinement and High-Performance of Equal-Channel Angular Pressed Cu-Mg Alloy for Electrical Contact Wire

open access: yesMetals, 2014
Multi-pass equal-channel angular pressing (EACP) was applied to produce ultrafine-grained (UFG) Cu-0.2wt%Mg alloy contact wire with high mechanical/electric performance, aim to overcome the catenary barrier of high-speed trains by maximizing the tension ...
Aibin Ma   +6 more
doaj   +1 more source

Fracture toughness testing data: A technology survey and bibliography [PDF]

open access: yes, 1975
Announced survey includes reports covering fracture toughness testing for various structural materials including information on plane strain and developing areas of mixed mode and plane strain test conditions.
Carpenter, J. L., Jr.   +3 more
core   +1 more source

Discrete Fourier Transform Improves the Prediction of the Electronic Properties of Molecules in Quantum Machine Learning

open access: yes, 2019
High-throughput approximations of quantum mechanics calculations and combinatorial experiments have been traditionally used to reduce the search space of possible molecules, drugs and materials.
Tchagang, Alain, Valdés, Julio
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

General Multi-Fidelity Framework for Training Artificial Neural Networks With Computational Models

open access: yesFrontiers in Materials, 2019
Training of artificial neural networks (ANNs) relies on the availability of training data. If ANNs have to be trained to predict or control the behavior of complex physical systems, often not enough real-word training data are available, for example ...
Roland Can Aydin   +3 more
doaj   +1 more source

Solving nonlinear third-order three-point boundary value problems by boundary shape functions methods

open access: yesAdvances in Difference Equations, 2021
For nonlinear third-order three-point boundary value problems (BVPs), we develop two algorithms to find solutions, which automatically satisfy the specified three-point boundary conditions.
Ji Lin, Yuhui Zhang, Chein-Shan Liu
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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