Results 41 to 50 of about 229,753 (219)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

On the impact of capillarity for strength at the nanoscale

Nature Communications, 2017
Nanoscale crystals can experience lattice instability and a tension-compression asymmetry of their strength. Here, Mameka and colleagues scrutinize the proposition that these phenomena arise from surface-induced stress, finding that the surface tension ...
Nadiia Mameka, Jürgen Markmann, Jörg Weissmüller   +2 more
doaj   +1 more source

Biodegradable Behaviors of Ultrafine-Grained ZE41A Magnesium Alloy in DMEM Solution

Metals, 2015
The main limitation to the clinical application of magnesium alloys is their too-fast degradation rate in the physiological environment. Bio-corrosion behaviors of the ZE41A magnesium alloy processed by multi-pass equal channel angular pressing (ECAP ...
Jinghua Jiang, Fan Zhang, Aibin Ma, Dan Song, Jianqing Chen, Huan Liu, Mingshan Qiang   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Adaptive plasticity of auxetic Kirigami hydrogel fabricated from anisotropic swelling of cellulose nanofiber film

Science and Technology of Advanced Materials
Hydrogels are flexible materials that typically accommodate elongation with positive Poisson’s ratios. Auxetic property, i.e., the negative Poisson’s ratio, of elastic materials can be macroscopically implemented by the structural design of the continuum.
Daisuke Nakagawa, Itsuo Hanasaki
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Stress Corrosion Cracking Behavior of Fine-Grained AZ61 Magnesium Alloys Processed by Equal-Channel Angular Pressing

Metals, 2017
The effect of equal-channel angular pressing (ECAP) on stress corrosion cracking (SCC) behavior of a cast AZ61 Mg alloy was investigated in distilled water (DW) using the slow strain rate tensile test (SSRT) at a strain rate of 1 × 10−6 s−1.
Qiuyuan Xie, Aibin Ma, Jinghua Jiang, Zhaojun Cheng, Dan Song, Yuchun Yuan, Huan Liu   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Grain Refinement and High-Performance of Equal-Channel Angular Pressed Cu-Mg Alloy for Electrical Contact Wire

Metals, 2014
Multi-pass equal-channel angular pressing (EACP) was applied to produce ultrafine-grained (UFG) Cu-0.2wt%Mg alloy contact wire with high mechanical/electric performance, aim to overcome the catenary barrier of high-speed trains by maximizing the tension ...
Aibin Ma, Chengcheng Zhu, Jianqing Chen, Jinghua Jiang, Dan Song, Shizhan Ni, Qing He   +6 more
doaj   +1 more source