Results 41 to 50 of about 275,739 (300)

On the role of tail in stability and energetic cost of bird flapping flight

open access: yesScientific Reports, 2022
Migratory birds travel over impressively long distances. Consequently, they have to adopt flight regimes being both efficient—in order to spare their metabolic resources—and robust to perturbations.
Gianmarco Ducci   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Fracture Mechanics-based Method for Prediction of Cracking of Circular and Elliptical Concrete Rings under Restrained Shrinkage [PDF]

open access: yes, 2014
This article has been made available through the Brunel Open Access Publishing Fund.A new experimental method, utilizing elliptical ring specimens, is developed for assessing the likelihood of cracking and cracking age of concrete subject to restrained ...
Dong, W   +5 more
core   +1 more source

From Mechanics to Machine Learning in Additive Manufacturing: A Review of Deformation, Fatigue, and Fracture

open access: yesTechnologies
Additive manufacturing (AM) enables a level of design flexibility that is difficult to achieve with conventional techniques, yet it inherently yields materials marked by significant variability, anisotropy, and sensitivity to defects that challenge ...
Murat Demiral, Murat Otkur
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Multimodal Microstructure and Mechanical Properties of AZ91 Mg Alloy Prepared by Equal Channel Angular Pressing plus Aging

open access: yesMetals, 2018
Developing cost-effective magnesium alloys with high strength and good ductility is a long-standing challenge for lightweight metals. Here we present a multimodal grain structured AZ91 Mg alloy with both high strength and good ductility, prepared through
Zhenquan Yang   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Futures in mechanics of structures and materials: proceedings of the 20th Australasian Conference on the Mechanics of Structures and Materials (ACMSM20), Toowoomba, Australia, 2-5 December 2008 [PDF]

open access: yes, 2009
Futures in Mechanics of Structures and Materials is a collection of peer-reviewed papers presented at the 20th Australasian Conference on the Mechanics of Structures and Materials (ACMSM20, University of Southern Queensland, Toowoomba, Queensland ...
Aravinthan, Thiru   +2 more
core  

Improving Strength and Ductility of a Mg-3.7Al-1.8Ca-0.4Mn Alloy with Refined and Dispersed Al2Ca Particles by Industrial-Scale ECAP Processing

open access: yesMetals, 2019
Tailoring the morphology and distribution of the Al2Ca second phase is important for improving mechanical properties of Al2Ca-containing Mg-Al-Ca based alloys.
Ce Wang   +7 more
doaj   +1 more source

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