Results 41 to 50 of about 955,420 (292)

Review of the Synergies Between Computational Modeling and Experimental Characterization of Materials Across Length Scales

, 2015
With the increasing interplay between experimental and computational approaches at multiple length scales, new research directions are emerging in materials science and computational mechanics.
Dingreville, Rémi, Karnesky, Richard A., Puel, Guillaume, Schmitt, Jean-Hubert   +3 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multimodal Microstructure and Mechanical Properties of AZ91 Mg Alloy Prepared by Equal Channel Angular Pressing plus Aging

Metals, 2018
Developing cost-effective magnesium alloys with high strength and good ductility is a long-standing challenge for lightweight metals. Here we present a multimodal grain structured AZ91 Mg alloy with both high strength and good ductility, prepared through
Zhenquan Yang, Aibin Ma, Huan Liu, Jiapeng Sun, Dan Song, Ce Wang, Yuchun Yuan, Jinghua Jiang   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Improving Strength and Ductility of a Mg-3.7Al-1.8Ca-0.4Mn Alloy with Refined and Dispersed Al₂Ca Particles by Industrial-Scale ECAP Processing

Metals, 2019
Tailoring the morphology and distribution of the Al2Ca second phase is important for improving mechanical properties of Al2Ca-containing Mg-Al-Ca based alloys.
Ce Wang, Aibin Ma, Jiapeng Sun, Xiaoru Zhuo, He Huang, Huan Liu, Zhenquan Yang, Jinghua Jiang   +7 more
doaj   +1 more source

Synchronous improvement in mechanical properties and corrosion resistance of Mg-Gd-Ag-Zr alloy through nanoprecipitates

Journal of Materials Research and Technology, 2023
It is still challenging to synchronously improve mechanical properties and corrosion resistance through one strategy during developing Mg alloys. Introducing high-density precipitates is an effective and popular approach to strengthen Mg alloys, while ...
Bangjun Li, Jiapeng Sun, An Xu, Bingqian Xu, Lingling Wang, Jie Yuan, Guosong Wu   +6 more
doaj   +1 more source

Control of hierarchical polymer mechanics with bioinspired metal-coordination dynamics. [PDF]

, 2015
In conventional polymer materials, mechanical performance is traditionally engineered via material structure, using motifs such as polymer molecular weight, polymer branching, or block copolymer design.
Barrett, Devin G, Cheng, Jing, Grindy, Scott C, Guan, Zhibin, Holten-Andersen, Niels, Learsch, Robert, Messersmith, Phillip B, Mozhdehi, Davoud   +7 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Fabrication of an Ultra-Fine Grained Pure Titanium with High Strength and Good Ductility via ECAP plus Cold Rolling

Metals, 2017
Microstructure evolutions and mechanical properties of a commercially pure titanium (CP-Ti, grade 2) during multi-pass rotary-die equal-channel angular pressing (RD-ECAP) and cold rolling (CR) were systematically investigated in this work, to achieve ...
Haoran Wu, Jinghua Jiang, Huan Liu, Jiapeng Sun, Yanxia Gu, Ren Tang, Xincan Zhao, Aibin Ma   +7 more
doaj   +1 more source

Notes and laboratory reports on “Technology of Structural materials and Material Science” Part 2 [PDF]

, 2017
“Technology of Structural materials and Material Science” is one of the basic technical disciplines in the syllabus for “Engineering mechanics” field of study.
Bodrova, L.G., Kramar, H.M.
core