Results 51 to 60 of about 275,739 (300)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Fracture mechanics of piezoelectric materials
, 1999 This paper presents an analysis of crack problems in homogeneous piezoelectrics or on the interfaces between two dissimilar piezoelectric materials based on the continuity of normal electric displacement and electric potential across the crack faces. The
Wang, TC (reprint author), Chinese Acad Sci, Inst Mech, LNM, Beijing 100080, Peoples R China. +2 more
core +1 more source
Dealloying-based interpenetrating-phase nanocomposites matching the elastic behavior of human bone
Scientific Reports, 2017 The long-term performance of orthopedic implants depends crucially on a close match between the mechanical behavior of bone and of the implant material. Yet, the present man-made materials with the required biocompatibility and strength are substantially
I. V. Okulov +2 more
doaj +1 more source
Metals, 2017 Microstructure evolutions and mechanical properties of a commercially pure titanium (CP-Ti, grade 2) during multi-pass rotary-die equal-channel angular pressing (RD-ECAP) and cold rolling (CR) were systematically investigated in this work, to achieve ...
Haoran Wu +7 more
doaj +1 more source
Journal of Materials Research and Technology, 2023 It is still challenging to synchronously improve mechanical properties and corrosion resistance through one strategy during developing Mg alloys. Introducing high-density precipitates is an effective and popular approach to strengthen Mg alloys, while ...
Bangjun Li +6 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
On the impact of capillarity for strength at the nanoscale
Nature Communications, 2017 Nanoscale crystals can experience lattice instability and a tension-compression asymmetry of their strength. Here, Mameka and colleagues scrutinize the proposition that these phenomena arise from surface-induced stress, finding that the surface tension ...
Nadiia Mameka +2 more
doaj +1 more source
Metals, 2016 A commercial AZ91D Mg alloy, after bulk grain refinement by various passes of equal-channel angular pressing (ECAP), was selected for micro-arc oxidation (MAO) in silicate electrolyte, corrosion testing in 3.5 wt % NaCl solution and morphology analyses ...
Aibin Ma +6 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source