Results 51 to 60 of about 832,948 (254)

On the impact of capillarity for strength at the nanoscale

open access: yesNature Communications, 2017
Nanoscale crystals can experience lattice instability and a tension-compression asymmetry of their strength. Here, Mameka and colleagues scrutinize the proposition that these phenomena arise from surface-induced stress, finding that the surface tension ...
Nadiia Mameka   +2 more
doaj   +1 more source

Multimodal Microstructure and Mechanical Properties of AZ91 Mg Alloy Prepared by Equal Channel Angular Pressing plus Aging

open access: yesMetals, 2018
Developing cost-effective magnesium alloys with high strength and good ductility is a long-standing challenge for lightweight metals. Here we present a multimodal grain structured AZ91 Mg alloy with both high strength and good ductility, prepared through
Zhenquan Yang   +7 more
doaj   +1 more source

A QM/MM approach for the study of monolayer-protected gold clusters

open access: yes, 2012
We report the development and implementation of hybrid methods that combine quantum mechanics (QM) with molecular mechanics (MM) to theoretically characterize thiolated gold clusters.
A Corma   +32 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Improving Strength and Ductility of a Mg-3.7Al-1.8Ca-0.4Mn Alloy with Refined and Dispersed Al2Ca Particles by Industrial-Scale ECAP Processing

open access: yesMetals, 2019
Tailoring the morphology and distribution of the Al2Ca second phase is important for improving mechanical properties of Al2Ca-containing Mg-Al-Ca based alloys.
Ce Wang   +7 more
doaj   +1 more source

Improving microstructure and corrosion resistance of LPSO-containing Mg–Y–Zn–Mn alloy through ECAP integrated with prior solution treatment

open access: yesJournal of Materials Research and Technology, 2022
Unique Mg-RE (rare earth) alloys with long-period stacking ordered (LPSO) structures have attracted extensive attention for their excellent mechanical properties and bright prospects. Thus it is urgent to improve their corrosion resistance simultaneously.
Yuxuan Yuan   +8 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Dealloying-based interpenetrating-phase nanocomposites matching the elastic behavior of human bone

open access: yesScientific Reports, 2017
The long-term performance of orthopedic implants depends crucially on a close match between the mechanical behavior of bone and of the implant material. Yet, the present man-made materials with the required biocompatibility and strength are substantially
I. V. Okulov   +2 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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