Results 71 to 80 of about 27,391 (258)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Three-body non-locality in particle decays

open access: yesJournal of High Energy Physics
The exploration of entanglement and Bell non-locality among multi-particle quantum systems offers a profound avenue for testing and understanding the limits of quantum mechanics and local real hidden variable theories.
Paweł Horodecki   +3 more
doaj   +1 more source

On the foundations of a new approach to statistical mechanics of classical systems

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1980
It has been known for a long time that the fundamental approaches to equilibrium and nonequillbrium statistical mechanics available at present lead to physical and mathematical inconsistencies for dense systems.
S. N. Bagghi
doaj   +1 more source

The Mechanics of the Systems of Structured Particles and Irreversibility

open access: yes, 2009
Dynamics of systems of structured particles consisting of potentially interacting material points is considered in the framework of classical mechanics. Equations of interaction and motion of structured particles have been derived. The expression for friction force has been obtained.
openaire   +2 more sources

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Coordinate Systems, Numerical Objects and Algorithmic Operations of Computational Experiment in Fluid Mechanics

open access: yesEPJ Web of Conferences, 2016
The paper deals with the computer implementation of direct computational experiments in fluid mechanics, constructed on the basis of the approach developed by the authors.
Degtyarev Alexander, Khramushin Vasily
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Time as a Quantum Observable, Canonically Conjugated to Energy, and Foundations of Self-Consistent Time Analysis of Quantum Processes

open access: yesAdvances in Mathematical Physics, 2009
Recent developments are reviewed and some new results are presented in the study of time in quantum mechanics and quantum electrodynamics as an observable, canonically conjugate to energy. This paper deals with the maximal Hermitian (but nonself-adjoint)
V. S. Olkhovsky
doaj   +1 more source

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