Results 121 to 130 of about 11,573,862 (305)
Cherenkov-drift emission mechanism [PDF]
Emission of a charged particle propagating in a medium with a curved magnetic field is reconsidered stressing the analogy between this emission mechanism and collective Cherenkov-type plasma emission.
Blandford, Roger +2 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Design and Analysis of Low-Gravity Simulation Scheme for Mars Ascent Vehicle
The sample carried back by the Mars Ascent Vehicle (MAV) is a potential flagship mission of deep space exploration in recent years. A low-gravity simulation experiment is an effective method and a necessary stage for verifying the performance of the MAV ...
Chen Li +4 more
doaj +1 more source
Redundant actuating mechanism Patent [PDF]
Design and development of release mechanism for spacecraft components, releasable despin weights, and extensible gravity ...
Madey, J. M., Moyer, X. W.
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The shale oil in the continental faulted basins in eastern China,represented by Jiyang shale oil,has made a breakthrough in production capacity. However,Jiyang shale oil faces great challenges in achieving high and stable production due to the large ...
YANG Yong +9 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

