Results 101 to 110 of about 2,036,755 (365)
ED100: Shifting Paradigms in Design Education and Student Thinking at KAIST [PDF]
, 2009 Organised by: Cranfield UniversityFreshman design courses offer a number of benefits to incoming students and are becoming increasingly popular in universities around the world.
Thompson, M. K.
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Optimal Combinatorial Mechanism Design [PDF]
We consider an optimal mechanism design problem with several heterogeneous objects and interdependent values. We characterize ex post incentives using an appropriate monotonicity condition and reformulate the problem in such a way that the choice of an ...
Levent Ulku
core
Constrained Bandwidth Allocation in Multi-Sensor Information Fusion: A Mechanism Design Approach
, 2005 Sensor networks are increasingly seen as a solution for a large number of environmental, security and military monitoring tasks. Typically, in these networks, noisy data from a number of local sensors is fused to reduce the uncertainty in the global ...
S. Reece +14 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
IEEE Transactions on Neural Systems and Rehabilitation EngineeringPostoperative rehabilitation is critical for restoring elbow function following fractures, yet current approaches face significant limitations. Manual rehabilitation lacks precision and relies heavily on subjective experience, while existing robotic ...
Qianze Helian +3 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The effect of music tempo on movement flow
Frontiers in PsychologyThere has been much controversy over the effects of music tempo on movement flow. In this study, a single-factor repeated-measurement design was used to explore the effect of music tempo (fast, slow, and no music control) on movement flow by measuring ...
Jian Zhang +7 more
doaj +1 more source
Kinematic analysis of a single-loop reconfigurable 7R mechanism with multiple operation modes [PDF]
, 2014 This paper presents a novel one-degree-of-freedom (1-DOF) single-loop reconfigurable 7R mechanism with multiple operation modes (SLR7RMMOM), composed of seven revolute (R) joints, via adding a revolute joint to the overconstrained Sarrus linkage.
Chablat, Damien +4 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source