Results 111 to 120 of about 13,763,508 (305)

Improving software development process through economic mechanism design [PDF]

open access: yes, 2010
We introduce the novel concept of applying economic mechanism design to software development process, and aim to find ways to adjust the incentives and disincentives of the software organization to align them with the motivations of the participants in ...
Collins, John   +12 more
core   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A Symmetrical Leech-Inspired Soft Crawling Robot Based on Gesture Control

open access: yesBiomimetics
This paper presents a novel soft crawling robot controlled by gesture recognition, aimed at enhancing the operability and adaptability of soft robots through natural human–computer interactions.
Jiabiao Li   +3 more
doaj   +1 more source

Optimal Combinatorial Mechanism Design [PDF]

open access: yes
We consider an optimal mechanism design problem with several heterogeneous objects and interdependent values. We characterize ex post incentives using an appropriate monotonicity condition and reformulate the problem in such a way that the choice of an ...
Levent Ulku
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

On Detail-Free Mechanism Design and Rationality [PDF]

open access: yes
The study of mechanism design is sometimes criticized, because the designed mechanisms depend on the fine detail of the model specification, and agents' behavior relies on the strong common knowledge assumptions on their rationality and others.
Hitoshi Matsushima
core   +2 more sources

A New Skeleton Model and the Motion Rhythm Analysis for Human Shoulder Complex Oriented to Rehabilitation Robotics

open access: yesApplied Bionics and Biomechanics, 2018
Rehabilitation robotics has become a widely accepted method to deal with the training of people with motor dysfunction. In robotics medium training, shoulder repeated exercise training has been proven beneficial for improving motion ability of human ...
Song Zhibin   +3 more
doaj   +1 more source

Human-centred mechanism design with Democratic AI. [PDF]

open access: yesNat Hum Behav, 2022
Koster R   +10 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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