Results 111 to 120 of about 1,837,363 (266)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Effect of Process Parameters on the Mechanical Properties of Simultaneous Double-Sided Friction Stir Welding Joints

open access: yesChinese Journal of Mechanical Engineering
Currently, conventional single-sided friction stir welding is primarily suitable for joining thin plate aluminum alloys, and its application to thick plates is still challenging in terms of welding efficiency and joint mechanical properties. Simultaneous
Shaofei Meng   +5 more
doaj   +1 more source

Static and Dynamic Performance Optimization of the AC Rotary Head Based on Stiffness-Mass Matching

open access: yesActuators
The AC rotary head, serving as a dual-axis direct-drive rotary actuation unit in five-axis CNC machine tools, integrates torque motors for A- and C-axis actuation, and its structural static and dynamic characteristics directly govern the actuation ...
Jiaming Liu   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Design and experiment of a Long Range Autonomous Underwater Vehicle for Ocean Acoustic Data Observation

open access: yesPolish Maritime Research
In order to realise noise measurement and target detection, this paper designs a long range autonomous underwater vehicle (LRAUV), namely ‘Petrel’, which contains a variable buoyancy system, attitude adjustment mechanisms, pitch and heading control ...
Sun Qindong   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Enhancing telesurgical safety with predictive digital twin synchronization: a framework for latency compensation in robotic surgery

open access: yesnpj Digital Medicine
This study addresses the critical challenge of master-slave latency in robot-assisted telesurgery by introducing a Digital Twin Visual Assistance (DTVA) system.
Hang Yuan   +11 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Matching IoT Devices to the Fog Service Providers: A Mechanism Design Perspective. [PDF]

open access: yesSensors (Basel), 2020
Bandyopadhyay A   +5 more
europepmc   +1 more source

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