Results 111 to 120 of about 4,576,095 (337)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Author Correction: The effects of text direction of different text lengths on Chinese reading

open access: yesScientific Reports, 2023
Yanqun Huang   +5 more
doaj   +1 more source

Research on Product Conceptual Design Scheme Configurations from a Designer–User Conflict Perspective

open access: yesApplied Sciences
In the context of rapid product iteration, design conflicts arise from discrepancies in designers’ understanding of user needs, influenced by subjective preferences, behavioural stances, and other factors.
Hongyu Shao   +3 more
doaj   +1 more source

Dynamic Optimization of Constrained Layer Damping Structure for the Headstock of Machine Tools with Modal Strain Energy Method

open access: yesShock and Vibration, 2017
Dynamic stiffness and damping of the headstock, which is a critical component of precision horizontal machining center, are two main factors that influence machining accuracy and surface finish quality. Constrained Layer Damping (CLD) structure is proved
Yakai Xu   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A Novel Flexible Endomicroscopic Scanning Instrument with Visual Servoing Control

open access: yesAdvanced Intelligent Systems
Optical biopsy using probe‐based confocal laser endomicroscopy (pCLE) and optical coherence tomography (OCT) technologies performs in vivo tissue scanning of organ surfaces and plays a crucial role in early cancer diagnosis.
Xingfeng Xu   +3 more
doaj   +1 more source

Dynamic Error Compensation for Ball Screw Feed Drive Systems Based on Prediction Model

open access: yesMachines
The dynamic error is the dominant factor affecting multi-axis CNC machining accuracy. Predicting and compensating for dynamic errors is vital in high-speed machining.
Hongda Liu   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy