Results 111 to 120 of about 23,050,020 (302)

Author Correction: The effects of text direction of different text lengths on Chinese reading

Scientific Reports, 2023
Yanqun Huang, Yifan Dong, Zhaojun Jiang, Peng Zhang, Jutao Li, Junyu Yang   +5 more
doaj   +1 more source

What mechanism design helps to realize the innovation function of maker-spaces: A qualitative comparative analysis based on fuzzy sets. [PDF]

PLoS One, 2022
Zheng J, Shi L, Jiang T.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Research on Product Conceptual Design Scheme Configurations from a Designer–User Conflict Perspective

Applied Sciences
In the context of rapid product iteration, design conflicts arise from discrepancies in designers’ understanding of user needs, influenced by subjective preferences, behavioural stances, and other factors.
Hongyu Shao, Sizhe Pan, Yufei Song, Quanfu Li   +3 more
doaj   +1 more source

Dynamic Optimization of Constrained Layer Damping Structure for the Headstock of Machine Tools with Modal Strain Energy Method

Shock and Vibration, 2017
Dynamic stiffness and damping of the headstock, which is a critical component of precision horizontal machining center, are two main factors that influence machining accuracy and surface finish quality. Constrained Layer Damping (CLD) structure is proved
Yakai Xu, Weiguo Gao, Yuhan Yu, Dawei Zhang, Xiangsong Zhao, Yanling Tian, Huaying Cun   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Enhancing telesurgical safety with predictive digital twin synchronization: a framework for latency compensation in robotic surgery

npj Digital Medicine
This study addresses the critical challenge of master-slave latency in robot-assisted telesurgery by introducing a Digital Twin Visual Assistance (DTVA) system.
Hang Yuan, Junjie Li, Bo Guan, Guangdi Chu, Wei Jiao, Hongzhi Zheng, Xingchi Liu, Jianchang Zhao, Jinhua Li, Jianmin Li, Xuecheng Yang, Haitao Niu   +11 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A Novel Flexible Endomicroscopic Scanning Instrument with Visual Servoing Control

Advanced Intelligent Systems
Optical biopsy using probe‐based confocal laser endomicroscopy (pCLE) and optical coherence tomography (OCT) technologies performs in vivo tissue scanning of organ surfaces and plays a crucial role in early cancer diagnosis.
Xingfeng Xu, Chengyu Zhang, Chi Zhang, Siyang Zuo   +3 more
doaj   +1 more source

Dynamic Error Compensation for Ball Screw Feed Drive Systems Based on Prediction Model

Machines
The dynamic error is the dominant factor affecting multi-axis CNC machining accuracy. Predicting and compensating for dynamic errors is vital in high-speed machining.
Hongda Liu, Yonghao Guo, Jiaming Liu, Wentie Niu   +3 more
doaj   +1 more source