Results 141 to 150 of about 1,385,207 (269)

Exploration of the Mechanism of Action of Dendrobium officinale in the Treatment of Liver Cancer Based on Network Pharmacology, Molecular Docking and in vitro Validation

Journal of Hepatocellular Carcinoma
Shuimeng Zhan,1,* Xinyan Lu,1,* Hongyan Guo,1 Yang Liu,1 Zhi Li,1 Wei Xu,2 Fang Xia,2 Huanjun Tang,2 Yi Tian,2 Jing Chen,3 Xuan Lin1 1Department of Endocrinology, CR & WISCO General Hospital Affiliated to Wuhan University of Science ...
Zhan S, Lu X, Guo H, Liu Y, Li Z, Xu W, Xia F, Tang H, Tian Y, Chen J, Lin X   +10 more
doaj  

Study on the Mechanism of Action of Baicalein in Inhibiting the Invasion of <i>Streptococcus agalactiae</i>. [PDF]

Antioxidants (Basel)
Jiang L, He X, Wang Y, Liu Y, Li X, Xu F.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

“Illuminating” Echinocandins’ Mechanism of Action

ACS Central Science, 2020
Boon Shing Loh, Wee Han Ang
doaj   +1 more source

Transarterial Embolization in Osteoarthritis of the Knee: Mechanism of Action and Current Results. [PDF]

Dtsch Arztebl Int
Collettini F, Fleckenstein FN, Winkler T, Wirtz DC, Perka C, Gebauer B.   +5 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Antimelanoma Activity of the Mastoparan Peptides MPX and MP1: Cellular Selectivity and Mechanism of Action. [PDF]

Mol Pharm
Sansone Semerdjian A, Arcisio-Miranda M.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Integrated omics reveal a unique antibacterial mechanism of action for the small molecule HSI#6. [PDF]

Curr Res Microb Sci
Sedky H, Hamed MB, Vermeire K, Schymkowitz J, Karamanou S, Economou A.   +5 more
europepmc   +1 more source

The Mechanism of Action of Hadacidin

Journal of Biological Chemistry, 1962
H T, SHIGEURA, C N, GORDON
openaire   +2 more sources