Results 211 to 220 of about 1,385,207 (269)

Ibrexafungerp: Mechanism of Action, Clinical, and Translational Science. [PDF]

Clin Transl Sci
Walley AH, Dupuis LN, Woodahl EL, Killam SR.   +3 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

The ubiquitin-proteasome system in Alzheimer's disease: mechanism of action and current status of treatment. [PDF]

Front Aging Neurosci
Jia S, Li Q, Rui X, Qin W, Zhang W, Dou J, Zhang X.   +6 more
europepmc   +1 more source

Mechanism of action of cisplatin on Na+/K+ ATPase of Caco-2 colon cells in vitro. [PDF]

PLoS One
Mourad R, Hodeify R, Kreydiyyeh S.
europepmc   +1 more source

Defining the Mechanism of Action and Resistance of New <i>Mycobacterium abscessus</i> MmpL3 Inhibitors. [PDF]

ACS Chem Biol
Abdalla BJ, Giletto MB, Goksel Carpa N, Wilson AK, Ellsworth E, Abramovitch RB.   +5 more
europepmc   +1 more source

The Pyrazole Scaffold in Anticancer Drug Discovery: A Review of Synthetic Approaches, Structure-Activity Relationships, and Target-Based Mechanism of Action. [PDF]

Int J Mol Sci
K R K, Hacholli VB, Gackowski M, Pisklak DM, Kumar A, Szeleszczuk Ł.   +5 more
europepmc   +1 more source

Study on the mechanism of action of HuaZhuoKeLi in modulating LCN2-mediated cellular pyroptosis to ameliorate ulcerative colitis. [PDF]

Sci Rep
Yang L, Wang S, Ma Y, Duan L, You J, Li B, Yang Y, Li D.   +7 more
europepmc   +1 more source

A Comparative Analysis of the Efficacy, Safety and Mechanism of Action of Flebogamma DIF, Fostamatinib and Romiplostim in Immune Thrombocytopenia. [PDF]

Life (Basel)
Akinyemi M, Ravi K, Tian F, Singh B.
europepmc   +1 more source

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Mechanisms of action of nitrates

Cardiovascular Drugs and Therapy, 1994
Glyceryl trinitrate, isosorbide dinitrate, and isosorbide-5-mononitrate are organic nitrate esters commonly used in the treatment of angina pectoris, myocardial infarction, and congestive heart failure. Organic nitrate esters have a direct relaxant effect on vascular smooth muscles, and the dilation of coronary vessels improves oxygen supply to the ...
K E, Torfgård, J, Ahlner
openaire   +2 more sources

Bisphosphonate mechanism of action

Current Rheumatology Reports, 2002
Nitrogen-containing bisphosphonates (N-BPs) are potent inhibitors of bone resorption widely used in the treatment of osteoporosis and other bone degrading disorders. At the tissue level, N-BPs reduce bone turnover, increase bone mass and mineralization, measured clinically as a rise in bone mineral density, increase bone strength and reduce fracture ...
Alfred A, Reszka, Gideon A, Rodan
openaire   +3 more sources