Results 51 to 60 of about 22,796,869 (307)

Mechanistic Models as Framework for Understanding Biomarker Disposition: Prediction of Creatinine‐Drug Interactions

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2020
Creatinine is widely used as a biomarker of glomerular filtration, and, hence, renal function. However, transporter‐mediated secretion also contributes to its renal clearance, albeit to a lesser degree.
D. Scotcher   +7 more
semanticscholar   +1 more source

Unification Strategies in Cognitive Science [PDF]

open access: yes, 2016
Cognitive science is an interdisciplinary conglomerate of various research fields and disciplines, which increases the risk of fragmentation of cognitive theories.
Miłkowski, Marcin
core   +3 more sources

Patient-Specific, Mechanistic Models of Tumor Growth Incorporating Artificial Intelligence and Big Data.

open access: yesAnnual Review of Biomedical Engineering
Despite the remarkable advances in cancer diagnosis, treatment, and management over the past decade, malignant tumors remain a major public health problem.
G. Lorenzo   +7 more
semanticscholar   +1 more source

A review of mechanistic models of viral dynamics in bat reservoirs for zoonotic disease

open access: yesPathogens and Global Health, 2020
The emergence of SARS-CoV-2, a coronavirus with suspected bat origins, highlights a critical need for heightened understanding of the mechanisms by which bats maintain potentially zoonotic viruses at the population level and transmit these pathogens ...
Anecia Gentles   +3 more
semanticscholar   +1 more source

Predictive ability of a process‐based versus a correlative species distribution model

open access: yesEcology and Evolution, 2020
Species distribution modeling is a widely used tool in many branches of ecology and evolution. Evaluations of the transferability of species distribution models—their ability to predict the distribution of species in independent data domains—are, however,
Steven I. Higgins   +4 more
doaj   +1 more source

Systems immunology: When systems biology meets immunology

open access: yesFrontiers in Immunology
The immune system is an intricate network of cells, proteins, and signaling pathways that coordinate protective responses and, when dysregulated, drive immune−related diseases.
Lucía Alfonso-González   +3 more
doaj   +1 more source

Detecting the impact of temperature on transmission of Zika, dengue, and chikungunya using mechanistic models

open access: yesPLoS Neglected Tropical Diseases, 2017
Recent epidemics of Zika, dengue, and chikungunya have heightened the need to understand the seasonal and geographic range of transmission by Aedes aegypti and Ae. albopictus mosquitoes.
E. Mordecai   +14 more
semanticscholar   +1 more source

How to Model Mechanistic Hierarchies [PDF]

open access: yesPhilosophy of Science, 2016
Mechanisms are usually viewed as hierarchical, with lower levels of a mechanism influencing, and decomposing, its higher-level behavior. To draw quantitative predictions from a model of a mechanism, the model must capture this hierarchical aspect. Recursive Bayesian networks (RBNs) were put forward by Lorenzo Casini et al.
openaire   +3 more sources

Mathematical Modeling to Estimate Photosynthesis: A State of the Art

open access: yesApplied Sciences, 2022
Photosynthesis is a process that indicates the productivity of crops. The estimation of this variable can be achieved through methods based on mathematical models. Mathematical models are usually classified as empirical, mechanistic, and hybrid.
Luz del Carmen García-Rodríguez   +6 more
doaj   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis   +9 more
wiley   +1 more source

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