Results 181 to 190 of about 584 (208)
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Journal of Molecular and Cellular Cardiology, 2021
Monocytes and macrophages are cellular forces that drive and resolve inflammation triggered by acute myocardial ischemia. One of the most important but least understood regulatory mechanisms is how these cells sense cues from the micro-milieu and integrate environmental signals with their response that eventually determines the outcome of myocardial ...
Vincent Phan +3 more
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Monocytes and macrophages are cellular forces that drive and resolve inflammation triggered by acute myocardial ischemia. One of the most important but least understood regulatory mechanisms is how these cells sense cues from the micro-milieu and integrate environmental signals with their response that eventually determines the outcome of myocardial ...
Vincent Phan +3 more
openaire +3 more sources
2022
The ability to culture embryos has created opportunities for animal agriculture, including the refined selection of superior genetics, and for the medical field, allowing couples experiencing infertility to have biological children. Moreover, culturing embryos has led to the generation of numerous genetically modified models for improving production ...
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The ability to culture embryos has created opportunities for animal agriculture, including the refined selection of superior genetics, and for the medical field, allowing couples experiencing infertility to have biological children. Moreover, culturing embryos has led to the generation of numerous genetically modified models for improving production ...
openaire +2 more sources
Mechanistic Target of Rapamycin Complex 1 in Distal Convoluted Tubule and Renal Potassium Handling
Journal of the American Society of NephrologyKey Points Rapamycin inhibited Kir4.1/Kir5.1, decreased Na-Cl-cotransporter (NCC), and increased renal potassium (K+) excretion.Inhibition of mechanistic target of rapamycin complex 1 in the distal convoluted tubule suppressed Kir4.1/Kir5.1, inhibited NCC, and increased renal K+ excretion.The ...
Yu Xiao +4 more
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Applied Physiology, Nutrition, and Metabolism, 2018
The mechanistic target of rapamycin complex-1 (mTORC-1) is a key nutrient and contraction-sensitive protein that regulates a pathway leading to skeletal muscle growth. Utilizing a multiplex assay, we aimed to examine the phosphorylation status of key mTORC-1-related signalling molecules in response to protein feeding and resistance exercise.
McGlory, Chris +4 more
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The mechanistic target of rapamycin complex-1 (mTORC-1) is a key nutrient and contraction-sensitive protein that regulates a pathway leading to skeletal muscle growth. Utilizing a multiplex assay, we aimed to examine the phosphorylation status of key mTORC-1-related signalling molecules in response to protein feeding and resistance exercise.
McGlory, Chris +4 more
openaire +3 more sources
2022
Understanding the underlying mechanisms of cell fate decisions in response to genetic and environmental factors will help to develop advanced stem cell therapies such as tissue regeneration or replacement of damaged or diseased cells. The social amoebae Dictyostelium discoideum is used as a lineage model which has a growth-to-development transition ...
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Understanding the underlying mechanisms of cell fate decisions in response to genetic and environmental factors will help to develop advanced stem cell therapies such as tissue regeneration or replacement of damaged or diseased cells. The social amoebae Dictyostelium discoideum is used as a lineage model which has a growth-to-development transition ...
openaire +1 more source
Sirtuins in mechanistic target of rapamycin complex 1 signaling
2021J. Burillo +5 more
openaire +1 more source
Clinical management of metastatic colorectal cancer in the era of precision medicine
Ca-A Cancer Journal for Clinicians, 2022Fortunato Ciardiello +2 more
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Radiation therapy‐associated toxicity: Etiology, management, and prevention
Ca-A Cancer Journal for Clinicians, 2021Kyle Wang
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Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Ca-A Cancer Journal for Clinicians, 2020Aaron J Grossberg +2 more
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The current state of molecular testing in the treatment of patients with solid tumors, 2019
Ca-A Cancer Journal for Clinicians, 2019John L Marshall +2 more
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